SLU7_EMENI
ID SLU7_EMENI Reviewed; 466 AA.
AC Q5B3U2; C8VAN0; Q3Y5U3;
DT 13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Pre-mRNA-splicing factor slu7;
DE AltName: Full=Splicing factor sluA;
GN Name=slu7; Synonyms=sluA; ORFNames=AN4788;
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Cha M.-J., Han K.-Y., Kwon N.-J., Han K.-H., Han D.-M., Chae S.-K.;
RT "Mutagen-inducible bidirectional uvsI promoter regulates both of the uvsI
RT and sluA gene expression in Aspergillus nidulans.";
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SLU7 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DQ157008; AAZ82408.1; -; Genomic_DNA.
DR EMBL; AACD01000081; EAA60358.1; -; Genomic_DNA.
DR EMBL; BN001303; CBF76780.1; -; Genomic_DNA.
DR RefSeq; XP_662392.1; XM_657300.1.
DR AlphaFoldDB; Q5B3U2; -.
DR SMR; Q5B3U2; -.
DR STRING; 162425.CADANIAP00005634; -.
DR EnsemblFungi; CBF76780; CBF76780; ANIA_04788.
DR EnsemblFungi; EAA60358; EAA60358; AN4788.2.
DR GeneID; 2872587; -.
DR KEGG; ani:AN4788.2; -.
DR VEuPathDB; FungiDB:AN4788; -.
DR eggNOG; KOG2560; Eukaryota.
DR HOGENOM; CLU_019317_3_1_1; -.
DR InParanoid; Q5B3U2; -.
DR OMA; KKPFYVD; -.
DR OrthoDB; 816947at2759; -.
DR Proteomes; UP000000560; Chromosome III.
DR Proteomes; UP000005890; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030628; F:pre-mRNA 3'-splice site binding; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR GO; GO:0008380; P:RNA splicing; IBA:GO_Central.
DR InterPro; IPR021715; Slu7_dom.
DR InterPro; IPR039974; Splicing_factor_SLU7.
DR PANTHER; PTHR12942; PTHR12942; 1.
DR Pfam; PF11708; Slu7; 1.
PE 3: Inferred from homology;
KW Metal-binding; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW Spliceosome; Zinc; Zinc-finger.
FT CHAIN 1..466
FT /note="Pre-mRNA-splicing factor slu7"
FT /id="PRO_0000218548"
FT ZN_FING 70..87
FT /note="CCHC-type"
FT REGION 147..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 395..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..450
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 466 AA; 53359 MW; 65DAA2C2B0AD829B CRC64;
MSRKPADVAS KERNEYIPAF ISKKPFYIDD DDTANDYLEH QRLHKQTTDQ SKWYERGKRA
GPAATKYRKG ACENCGAMTH KAKECLSRPR KHGAKWTGKD IQADEVIQNV DLGWDAKRDR
WNGYDAAEYR QVVEEYEELE RLKRQAKLTK GETQTTNDGL DDEAPEQEAR YAEESDMGRQ
QSTATRNLRI REDTAKYLLN LDLDSAKYDP KTRRMVDMGA AEDQAAALVA EENFVRSSGD
AAEFERAQRY AWEAQERGTQ KIHLQANPTS GEITRKKELA ESEAKRDAHR KALLEKYGGE
QHLKHTPLLE TMVVENERFV EYDETGAIKG APKKATKSKY PEDILTNNHK SVWGSWWHNF
QWGYACCFST VKNSYCTGEE GKRAFEEARN MLLLPGDETE QPSLAVESAS RQEEPSAESH
NQQRDSKKRT LMEVQSGITE EELESYKRSR LAADDPMAAF IEKDDS
