ID   SLU7_NEUCR              Reviewed;         416 AA.
AC   Q7SDY6;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Pre-mRNA-splicing factor slu-7;
GN   Name=slu-7; ORFNames=NCU01950;
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA   Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA   Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA   Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA   Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA   Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA   Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SLU7 family. {ECO:0000305}.
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DR   EMBL; CM002236; EAA34998.1; -; Genomic_DNA.
DR   RefSeq; XP_964234.1; XM_959141.2.
DR   AlphaFoldDB; Q7SDY6; -.
DR   SMR; Q7SDY6; -.
DR   STRING; 5141.EFNCRP00000001173; -.
DR   PRIDE; Q7SDY6; -.
DR   EnsemblFungi; EAA34998; EAA34998; NCU01950.
DR   GeneID; 3880383; -.
DR   KEGG; ncr:NCU01950; -.
DR   VEuPathDB; FungiDB:NCU01950; -.
DR   HOGENOM; CLU_019317_3_1_1; -.
DR   InParanoid; Q7SDY6; -.
DR   Proteomes; UP000001805; Chromosome 1, Linkage Group I.
DR   GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0030628; F:pre-mRNA 3'-splice site binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR   GO; GO:0008380; P:RNA splicing; IBA:GO_Central.
DR   InterPro; IPR021715; Slu7_dom.
DR   InterPro; IPR039974; Splicing_factor_SLU7.
DR   InterPro; IPR001878; Znf_CCHC.
DR   PANTHER; PTHR12942; PTHR12942; 1.
DR   Pfam; PF11708; Slu7; 1.
DR   PROSITE; PS50158; ZF_CCHC; 1.
PE   3: Inferred from homology;
KW   Metal-binding; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Spliceosome; Zinc; Zinc-finger.
FT   CHAIN           1..416
FT                   /note="Pre-mRNA-splicing factor slu-7"
FT                   /id="PRO_0000218551"
FT   ZN_FING         95..112
FT                   /note="CCHC-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   REGION          1..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          168..213
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   416 AA;  46417 MW;  B372B572488C4605 CRC64;
     MPPPPPNRRE QATAAPSSTD KSETGAGAAR KEDNIYIPSY ISKQPFYVSG LDNEEGDSLL
     HQRARQQEED KAAQAAALLA RGKKAGPART KWVKGACENC GAMGHKKKDC LERPRKFGAK
     ATGKDIQADR IVRDVKLGYE AKRDVYSAYD PKQYMEVVEE YNMLEEARRA LQGDQKTPDG
     EGADGPEDDK SGFKYDEESD MGRDRATTKQ SMRIREDTAK YLLNLDSDSA KYNPKKRALV
     DAGAIADKSA ALFAEESFLR ASGEAAEFEK AQRYAWEAQE RSGDTSLHLQ ANPTAGEILR
     KKESEEREAK RRKRAEELAN QYGTQPVISD ALRETIKESE TFVEYDEAGL IKGAPKKVGK
     SKYLEDVYIN NHTSVWGSWW SDFRWGYACC HSFVKNSYCT GEAGIAASEK ADAWDK