ID   SLU7_YARLI              Reviewed;         416 AA.
AC   Q6C9T0;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Pre-mRNA-splicing factor SLU7;
GN   Name=SLU7; OrderedLocusNames=YALI0D08624g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SLU7 family. {ECO:0000305}.
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DR   EMBL; CR382130; CAG80770.1; -; Genomic_DNA.
DR   RefSeq; XP_502582.1; XM_502582.1.
DR   AlphaFoldDB; Q6C9T0; -.
DR   STRING; 4952.CAG80770; -.
DR   PRIDE; Q6C9T0; -.
DR   EnsemblFungi; CAG80770; CAG80770; YALI0_D08624g.
DR   GeneID; 2910713; -.
DR   KEGG; yli:YALI0D08624g; -.
DR   VEuPathDB; FungiDB:YALI0_D08624g; -.
DR   HOGENOM; CLU_019317_3_1_1; -.
DR   InParanoid; Q6C9T0; -.
DR   OMA; KKPFYVD; -.
DR   Proteomes; UP000001300; Chromosome D.
DR   GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030628; F:pre-mRNA 3'-splice site binding; IEA:InterPro.
DR   GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IEA:EnsemblFungi.
DR   GO; GO:0008380; P:RNA splicing; IBA:GO_Central.
DR   InterPro; IPR021715; Slu7_dom.
DR   InterPro; IPR039974; Splicing_factor_SLU7.
DR   PANTHER; PTHR12942; PTHR12942; 1.
DR   Pfam; PF11708; Slu7; 2.
PE   3: Inferred from homology;
KW   Metal-binding; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Spliceosome; Zinc; Zinc-finger.
FT   CHAIN           1..416
FT                   /note="Pre-mRNA-splicing factor SLU7"
FT                   /id="PRO_0000218553"
FT   ZN_FING         119..136
FT                   /note="CCHC-type"
FT   REGION          1..114
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..45
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        80..114
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   416 AA;  46937 MW;  749C29E45729E442 CRC64;
     MSKPATTLDG LQDGSVELQK RLSAKRDAEG ELKHEEDRKL RKEGKTQTPV TNQEGDVLNP
     YIPRFMSSAP WYAKAGDDDP SASSLDHLKK DKTDSKKEEW YARGQDRSSL ERPKKFRKGA
     CENCGAMTHK KKDCMERPRK VGAKYKADNL QADDVISNPH MSWDSKRDRW NGYDAEDFKR
     VIDEHNMTEE LQKKLHGDAP AETDAEKAAA VEEAIRKSTR TLRLREDTAV YLKDLNSETV
     YNPGSRTFRT ADEGYIDKDG MFVRHTTGEG KEMEELTRIA EAESALGNQI HLHANPTAAA
     IAAKRIKEEA EKAKDAEKRA LEEKYGKQDH VRVRPKEYTS VVTAKKPTVI RAKNAQGIAV
     SKYEEDVFPG NHTSVWGSYY DKETAKWGYA CCHCLIKNGY CVGEKGKKKK GAMDTV