ID   BICL1_XENTR             Reviewed;         599 AA.
AC   Q0V9T6;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=BICD family-like cargo adapter 1;
DE   AltName: Full=Bicaudal D-related protein 1;
DE            Short=BICD-related protein 1;
DE            Short=BICDR-1;
DE   AltName: Full=Coiled-coil domain-containing protein 64A;
GN   Name=bicdl1; Synonyms=bicdr1, ccdc64;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of secretory vesicle machinery in developing
CC       neurons that acts as a regulator of neurite outgrowth. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000250}. Note=Localizes around the centrosome.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BICDR family. {ECO:0000305}.
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DR   EMBL; BC121401; AAI21402.1; -; mRNA.
DR   RefSeq; NP_001072328.1; NM_001078860.1.
DR   AlphaFoldDB; Q0V9T6; -.
DR   SMR; Q0V9T6; -.
DR   STRING; 8364.ENSXETP00000026607; -.
DR   PaxDb; Q0V9T6; -.
DR   PRIDE; Q0V9T6; -.
DR   DNASU; 779781; -.
DR   GeneID; 779781; -.
DR   KEGG; xtr:779781; -.
DR   CTD; 92558; -.
DR   Xenbase; XB-GENE-5811431; bicdl1.
DR   eggNOG; ENOG502QUA9; Eukaryota.
DR   HOGENOM; CLU_029068_0_0_1; -.
DR   InParanoid; Q0V9T6; -.
DR   OMA; IDMHELI; -.
DR   OrthoDB; 595515at2759; -.
DR   TreeFam; TF326671; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000012189; Expressed in 2-cell stage embryo and 11 other tissues.
DR   ExpressionAtlas; Q0V9T6; baseline and differential.
DR   GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0034452; F:dynactin binding; ISS:UniProtKB.
DR   GO; GO:0031267; F:small GTPase binding; ISS:UniProtKB.
DR   GO; GO:0055107; P:Golgi to secretory granule transport; ISS:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0047496; P:vesicle transport along microtubule; IBA:GO_Central.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Neurogenesis; Reference proteome;
KW   Transport.
FT   CHAIN           1..599
FT                   /note="BICD family-like cargo adapter 1"
FT                   /id="PRO_0000302860"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          352..375
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          80..341
FT                   /evidence="ECO:0000255"
FT   COILED          405..536
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        352..374
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   599 AA;  69257 MW;  8115F83424B617F9 CRC64;
     MELPISFLSD SSRPAASSER GDQAALGRGE LEFDEELVFL AAEGEGDPEE IEGPEVREQS
     ELLCIIRQKE KDLVLAARLG KALLERNQDM SRRYEEMQRE MTDKLEHLEQ EKHELKRKLE
     NREGEWEGRV SELESDVKLL QEELEKQQVN LREADREKLS VVQELSEQNQ RLLEQLSRAT
     EMERQLSQQV NVLQEEFREK SLSTSQHVSR LESLLAEIKM LSDRKRELEQ QLSTIMEENE
     QLQGLVEELQ DKELSLNQQN FGKDLQLRES QLEIEEMRLS YRQLEGKLEE LREEKSLQHM
     NSTSTSLLSE IEQSIEAEEQ EQEREQLRLQ LWEAHCQVRS LCCQLRGNES ADSAVSTDSS
     MDESSETSSA KDVPAGSLRT ALSELKSLIL SILETCDSAS SRKCEDDGLE EQIKQTSEDS
     RALRELLQGE QMRMKQTFDE LQELHKQVTL LSVEMNALKE ERDRLLVLTQ NDETQEQLMK
     AIKDRDEAIS KKTAVELELA KCRIDLMSLN TQLLDAIQQK LNLSQQLEAW QDDMHRVIDQ
     QLMDKHQKEW SQPAYSFSNS HHVKQCSKAA AMKHAERPGE ESIGAEGRRL FSFLKKTKC