SLX9_ASHGO
ID SLX9_ASHGO Reviewed; 188 AA.
AC Q758S2;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 79.
DE RecName: Full=Ribosome biogenesis protein SLX9;
GN Name=SLX9; OrderedLocusNames=AEL319C;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Involved in ribosome biogenesis. Required for normal pre-rRNA
CC processing in internal transcribed spacer 1 (ITS1). May be involved in
CC the movements of the replication forks (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with the 35S, 23S and 20S pre-rRNAs and with the U3
CC snoRNA. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SLX9 family. {ECO:0000305}.
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DR EMBL; AE016818; AAS52365.1; -; Genomic_DNA.
DR RefSeq; NP_984541.1; NM_209894.1.
DR AlphaFoldDB; Q758S2; -.
DR STRING; 33169.AAS52365; -.
DR EnsemblFungi; AAS52365; AAS52365; AGOS_AEL319C.
DR GeneID; 4620711; -.
DR KEGG; ago:AGOS_AEL319C; -.
DR eggNOG; ENOG502S2IS; Eukaryota.
DR HOGENOM; CLU_1372424_0_0_1; -.
DR InParanoid; Q758S2; -.
DR OMA; LKPKMQD; -.
DR Proteomes; UP000000591; Chromosome V.
DR GO; GO:0030686; C:90S preribosome; IEA:EnsemblFungi.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0030688; C:preribosome, small subunit precursor; IEA:EnsemblFungi.
DR GO; GO:0032040; C:small-subunit processome; IEA:EnsemblFungi.
DR GO; GO:0051880; F:G-quadruplex DNA binding; IEA:EnsemblFungi.
DR GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0000056; P:ribosomal small subunit export from nucleus; IEA:EnsemblFungi.
DR InterPro; IPR028160; Slx9-like.
DR Pfam; PF15341; SLX9; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..188
FT /note="Ribosome biogenesis protein SLX9"
FT /id="PRO_0000333447"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 188 AA; 21526 MW; F32537A17ECBFF01 CRC64;
MVAKKRTQLR AKAMRQRRNS SEAMETEELP PDPKAFLHQL RESKREKQLN RSQSFLNRLR
DQAGNGGISK SALRRRKKRM KEELKPRMED LLTSLKEEGV LEEDESGELA AVTGVTAITA
SNGYSGLHDT AEACGTVRIR KNEPSIRTQR GAKLLTTKEQ ERFTKVISNE RFRSSPFETL
REIIKSRK
