ID   SLX9_KLULA              Reviewed;         198 AA.
AC   Q6CT43;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Ribosome biogenesis protein SLX9;
GN   Name=SLX9; OrderedLocusNames=KLLA0C15565g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in ribosome biogenesis. Required for normal pre-rRNA
CC       processing in internal transcribed spacer 1 (ITS1). May be involved in
CC       the movements of the replication forks (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with the 35S, 23S and 20S pre-rRNAs and with the U3
CC       snoRNA. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SLX9 family. {ECO:0000305}.
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DR   EMBL; CR382123; CAH01747.1; -; Genomic_DNA.
DR   RefSeq; XP_452896.1; XM_452896.1.
DR   AlphaFoldDB; Q6CT43; -.
DR   SMR; Q6CT43; -.
DR   STRING; 28985.XP_452896.1; -.
DR   EnsemblFungi; CAH01747; CAH01747; KLLA0_C15565g.
DR   GeneID; 2891926; -.
DR   KEGG; kla:KLLA0_C15565g; -.
DR   eggNOG; ENOG502S2IS; Eukaryota.
DR   HOGENOM; CLU_1372424_0_0_1; -.
DR   InParanoid; Q6CT43; -.
DR   OMA; LKPKMQD; -.
DR   Proteomes; UP000000598; Chromosome C.
DR   GO; GO:0030686; C:90S preribosome; IEA:EnsemblFungi.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0030688; C:preribosome, small subunit precursor; IEA:EnsemblFungi.
DR   GO; GO:0032040; C:small-subunit processome; IEA:EnsemblFungi.
DR   GO; GO:0051880; F:G-quadruplex DNA binding; IEA:EnsemblFungi.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:0000056; P:ribosomal small subunit export from nucleus; IEA:EnsemblFungi.
DR   InterPro; IPR028160; Slx9-like.
DR   Pfam; PF15341; SLX9; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..198
FT                   /note="Ribosome biogenesis protein SLX9"
FT                   /id="PRO_0000333450"
FT   REGION          27..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          137..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   198 AA;  22503 MW;  AB41BC861DF7D8F3 CRC64;
     MVAKKRTALR TKAAKVTTVE KDHAVQPLTE LPPDPKAFLH QPRETKKEKL QNKSQNFISR
     ITDVGKNLTG ISKSSVRRRK RKLRDELKPK MDDLLISLQQ EGVIRNDEPS QEDLAVEKKA
     SLNSSVTKVI TSDAYGSIRG SAPQHKGQLR KNEPNIRNQR GAKALAQQES KRFNEVLLNE
     TFQKNPFDAL KEAIRMRQ