SLX9_PICST
ID SLX9_PICST Reviewed; 194 AA.
AC A3LVY7;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-JUL-2007, sequence version 2.
DT 25-MAY-2022, entry version 53.
DE RecName: Full=Ribosome biogenesis protein SLX9;
GN Name=SLX9; ORFNames=PICST_32290;
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- FUNCTION: Involved in ribosome biogenesis. Required for normal pre-rRNA
CC processing in internal transcribed spacer 1 (ITS1). May be involved in
CC the movements of the replication forks (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with the 35S, 23S and 20S pre-rRNAs and with the U3
CC snoRNA. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SLX9 family. {ECO:0000305}.
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DR EMBL; CP000499; ABN67201.2; -; Genomic_DNA.
DR RefSeq; XP_001385230.2; XM_001385193.1.
DR AlphaFoldDB; A3LVY7; -.
DR STRING; 4924.XP_001385230.2; -.
DR EnsemblFungi; ABN67201; ABN67201; PICST_32290.
DR GeneID; 4839074; -.
DR KEGG; pic:PICST_32290; -.
DR eggNOG; ENOG502S2IS; Eukaryota.
DR HOGENOM; CLU_126135_0_0_1; -.
DR InParanoid; A3LVY7; -.
DR OMA; LKPKMQD; -.
DR OrthoDB; 1594718at2759; -.
DR Proteomes; UP000002258; Chromosome 5.
DR GO; GO:0030686; C:90S preribosome; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0030688; C:preribosome, small subunit precursor; IEA:InterPro.
DR GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:InterPro.
DR InterPro; IPR028160; Slx9-like.
DR Pfam; PF15341; SLX9; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..194
FT /note="Ribosome biogenesis protein SLX9"
FT /id="PRO_0000333451"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 194 AA; 21856 MW; 7AB507DB35B80C97 CRC64;
MAGGIRKKTS LRDKSSRKSG LASKISEFKQ QSTIENGQDE HFHENPLLKL SKISKKEKQQ
QKTDTFNQKL LHKVTFNTSS NISKSAVRRR KRKEKEQLKP KMDELLTSLP DDMFAPTAAS
TTTIRRATKT GEATSGYVKS TKANLNLPNA NKATGHKQIL KQENKNFTNV LKNPEFRQSP
FSALKNAIKE NLQG