SLX9_VANPO
ID SLX9_VANPO Reviewed; 206 AA.
AC A7TKU9;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-OCT-2007, sequence version 1.
DT 25-MAY-2022, entry version 45.
DE RecName: Full=Ribosome biogenesis protein SLX9;
GN Name=SLX9; ORFNames=Kpol_1025p24;
OS Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX NCBI_TaxID=436907;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC Y-8283 / UCD 57-17;
RX PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT species descended from a whole-genome duplication.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC -!- FUNCTION: Involved in ribosome biogenesis. Required for normal pre-rRNA
CC processing in internal transcribed spacer 1 (ITS1). May be involved in
CC the movements of the replication forks (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with the 35S, 23S and 20S pre-rRNAs and with the U3
CC snoRNA. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SLX9 family. {ECO:0000305}.
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DR EMBL; DS480410; EDO17104.1; -; Genomic_DNA.
DR RefSeq; XP_001644962.1; XM_001644912.1.
DR AlphaFoldDB; A7TKU9; -.
DR STRING; 436907.A7TKU9; -.
DR EnsemblFungi; EDO17104; EDO17104; Kpol_1025p24.
DR GeneID; 5545296; -.
DR KEGG; vpo:Kpol_1025p24; -.
DR eggNOG; ENOG502S2IS; Eukaryota.
DR HOGENOM; CLU_1372424_0_0_1; -.
DR InParanoid; A7TKU9; -.
DR OMA; LKPKMQD; -.
DR OrthoDB; 1561815at2759; -.
DR PhylomeDB; A7TKU9; -.
DR Proteomes; UP000000267; Unassembled WGS sequence.
DR GO; GO:0030686; C:90S preribosome; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0030688; C:preribosome, small subunit precursor; IEA:InterPro.
DR GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:InterPro.
DR InterPro; IPR028160; Slx9-like.
DR Pfam; PF15341; SLX9; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..206
FT /note="Ribosome biogenesis protein SLX9"
FT /id="PRO_0000333453"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 105..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..52
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 206 AA; 23416 MW; 6A2D1E647A756180 CRC64;
MVAKKRNTLR SKAAAGRNAK TSVLEDSVLN ELPPDPKAFL HQHRESKRDK QNTKQQSFLS
QIKNKSLGLD SNLAGISKSA ARRRKRKIRD DLKPKMGELL TSLEKEEDLK EYTQDQDDSK
DADGDEQMEI SINNVTKITK SNKYGKLSHE LPGSVKIKKN QPSIRNQKGA KQLAIDESKR
FNQVLTNQSF QQNPFGSLRE IIKMQK