SLX9_YEAS7
ID SLX9_YEAS7 Reviewed; 210 AA.
AC A6ZV63;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-SEP-2007, sequence version 1.
DT 03-AUG-2022, entry version 39.
DE RecName: Full=Ribosome biogenesis protein SLX9;
GN Name=SLX9; ORFNames=SCY_2296;
OS Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=307796;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YJM789;
RX PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA Steinmetz L.M.;
RT "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT strain YJM789.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC -!- FUNCTION: Involved in ribosome biogenesis. Required for normal pre-rRNA
CC processing in internal transcribed spacer 1 (ITS1). May be involved in
CC the movements of the replication forks (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with the 35S, 23S and 20S pre-rRNAs and with the U3
CC snoRNA. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- INDUCTION: Transiently up-regulated during the initial 15 minutes of
CC dough-fermentation. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SLX9 family. {ECO:0000305}.
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DR EMBL; AAFW02000102; EDN61671.1; -; Genomic_DNA.
DR AlphaFoldDB; A6ZV63; -.
DR PRIDE; A6ZV63; -.
DR EnsemblFungi; EDN61671; EDN61671; SCY_2296.
DR HOGENOM; CLU_1372424_0_0_1; -.
DR Proteomes; UP000007060; Unassembled WGS sequence.
DR GO; GO:0030686; C:90S preribosome; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0030688; C:preribosome, small subunit precursor; IEA:InterPro.
DR GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:InterPro.
DR InterPro; IPR028160; Slx9-like.
DR Pfam; PF15341; SLX9; 1.
PE 3: Inferred from homology;
KW Nucleus; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..210
FT /note="Ribosome biogenesis protein SLX9"
FT /id="PRO_0000333452"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 210 AA; 24009 MW; FB7E115D7F32C7A3 CRC64;
MVAKKRNTLR SKASARNSQN FGPDVANNGI LDESYDIESD PRAFLHQPKE TKKEKLLNRQ
NTFLSNLKGK STLSDGIGAN FDGISKSSIR RRKRKLREEL KPRMQDLLTS LEQEKDLRGI
IENSSKDMNN DDDIDMDSKI RFVDTKEMNL KKIEPGSVRI KKNQPNIRNQ KGAKALAANE
TARFNQVLTN QDFQKNPFGA LREVIKLQKH