ID   SLY1_ARATH              Reviewed;         627 AA.
AC   Q9SL48;
DT   01-FEB-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 135.
DE   RecName: Full=SEC1 family transport protein SLY1;
DE            Short=AtSLY1;
GN   Name=SLY1; OrderedLocusNames=At2g17980; ORFNames=T27K22.15;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=19376835; DOI=10.1104/pp.109.138677;
RA   Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA   Grossmann J., Gruissem W., Baginsky S.;
RT   "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT   chloroplast kinase substrates and phosphorylation networks.";
RL   Plant Physiol. 150:889-903(2009).
CC   -!- FUNCTION: May be involved in the early secretory pathway.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family. {ECO:0000305}.
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DR   EMBL; AC006201; AAD20128.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC06711.1; -; Genomic_DNA.
DR   EMBL; AY050414; AAK91430.1; -; mRNA.
DR   EMBL; AY059659; AAL31152.1; -; mRNA.
DR   PIR; G84558; G84558.
DR   RefSeq; NP_179389.1; NM_127354.5.
DR   AlphaFoldDB; Q9SL48; -.
DR   SMR; Q9SL48; -.
DR   BioGRID; 1667; 1.
DR   IntAct; Q9SL48; 3.
DR   STRING; 3702.AT2G17980.1; -.
DR   iPTMnet; Q9SL48; -.
DR   PaxDb; Q9SL48; -.
DR   PRIDE; Q9SL48; -.
DR   ProteomicsDB; 232639; -.
DR   EnsemblPlants; AT2G17980.1; AT2G17980.1; AT2G17980.
DR   GeneID; 816310; -.
DR   Gramene; AT2G17980.1; AT2G17980.1; AT2G17980.
DR   KEGG; ath:AT2G17980; -.
DR   Araport; AT2G17980; -.
DR   TAIR; locus:2060954; AT2G17980.
DR   eggNOG; KOG1301; Eukaryota.
DR   HOGENOM; CLU_016216_3_1_1; -.
DR   InParanoid; Q9SL48; -.
DR   OMA; DRQLDNF; -.
DR   OrthoDB; 917326at2759; -.
DR   PhylomeDB; Q9SL48; -.
DR   PRO; PR:Q9SL48; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q9SL48; baseline and differential.
DR   Genevisible; Q9SL48; AT.
DR   GO; GO:0000139; C:Golgi membrane; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR   GO; GO:0019905; F:syntaxin binding; IBA:GO_Central.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR   Gene3D; 3.40.50.1910; -; 1.
DR   Gene3D; 3.40.50.2060; -; 1.
DR   Gene3D; 3.90.830.10; -; 1.
DR   InterPro; IPR043154; Sec-1-like_dom1.
DR   InterPro; IPR043127; Sec-1-like_dom3a.
DR   InterPro; IPR001619; Sec1-like.
DR   InterPro; IPR027482; Sec1-like_dom2.
DR   InterPro; IPR036045; Sec1-like_sf.
DR   PANTHER; PTHR11679; PTHR11679; 1.
DR   Pfam; PF00995; Sec1; 1.
DR   PIRSF; PIRSF005715; VPS45_Sec1; 1.
DR   SUPFAM; SSF56815; SSF56815; 1.
PE   1: Evidence at protein level;
KW   Protein transport; Reference proteome; Transport.
FT   CHAIN           1..627
FT                   /note="SEC1 family transport protein SLY1"
FT                   /id="PRO_0000206298"
FT   REGION          526..551
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   627 AA;  69151 MW;  FFE59216BF1B7337 CRC64;
     MALNLRQKQT ECVIRMLNLN QPLNPSGTAN EEVYKILIYD RFCQNILSPL THVKDLRKHG
     VTLFFLIDKD RQPVHDVPAV YFVQPTESNL QRIIADASRS LYDTFHLNFS SSIPRKFLEE
     LASGTLKSGS VEKVSKVHDQ YLEFVTLEDN LFSLAQQSTY VQMNDPSAGE KEINEIIERV
     ASGLFCVLVT LGVVPVIRCP SGGPAEMVAS LLDQKLRDHL LSKNNLFTEG GGFMSSFQRP
     LLCIFDRNFE LSVGIQHDFR YRPLVHDVLG LKLNQLKVQG EKGPPKSFEL DSSDPFWSAN
     STLEFPDVAV EIETQLNKYK RDVEEVNKKT GGGSGAEFDG TDLIGNIHTE HLMNTVKSLP
     ELTERKKVID KHTNIATALL GQIKERSIDA FTKKESDMMM RGGIDRTELM AALKGKGTKM
     DKLRFAIMYL ISTETINQSE VEAVEAALNE AEADTSAFQY VKKIKSLNAS FAATSANSAS
     RSNIVDWAEK LYGQSISAVT AGVKNLLSSD QQLAVTRTVE ALTEGKPNPE IDSYRFLDPR
     APKSSSSGGS HVKGPFREAI VFMIGGGNYV EYGSLQELTQ RQLTVKNVIY GATEILNGGE
     LVEQLGLLGK KMGLGGPVAS TSLSGGH