ID   SLYA_YERE8              Reviewed;         143 AA.
AC   A1JNY1;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Transcriptional regulator SlyA {ECO:0000255|HAMAP-Rule:MF_01819};
GN   Name=slyA {ECO:0000255|HAMAP-Rule:MF_01819}; OrderedLocusNames=YE2144;
OS   Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 /
OS   8081).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=393305;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 13174 / 8081;
RX   PubMed=17173484; DOI=10.1371/journal.pgen.0020206;
RA   Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L.,
RA   Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T.,
RA   Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S.,
RA   Sanders M., Whitehead S., Quail M.A., Dougan G., Parkhill J.,
RA   Prentice M.B.;
RT   "The complete genome sequence and comparative genome analysis of the high
RT   pathogenicity Yersinia enterocolitica strain 8081.";
RL   PLoS Genet. 2:2039-2051(2006).
CC   -!- FUNCTION: Transcription regulator that can specifically activate or
CC       repress expression of target genes. {ECO:0000255|HAMAP-Rule:MF_01819}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01819}.
CC   -!- SIMILARITY: Belongs to the SlyA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01819}.
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DR   EMBL; AM286415; CAL12214.1; -; Genomic_DNA.
DR   RefSeq; WP_004706617.1; NC_008800.1.
DR   RefSeq; YP_001006384.1; NC_008800.1.
DR   AlphaFoldDB; A1JNY1; -.
DR   SMR; A1JNY1; -.
DR   STRING; 393305.YE2144; -.
DR   EnsemblBacteria; CAL12214; CAL12214; YE2144.
DR   GeneID; 67418214; -.
DR   KEGG; yen:YE2144; -.
DR   PATRIC; fig|393305.7.peg.2308; -.
DR   eggNOG; COG1846; Bacteria.
DR   HOGENOM; CLU_083287_18_2_6; -.
DR   OMA; CSNDRRA; -.
DR   Proteomes; UP000000642; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_01819; HTH_type_SlyA; 1.
DR   InterPro; IPR000835; HTH_MarR-typ.
DR   InterPro; IPR023187; Tscrpt_reg_MarR-type_CS.
DR   InterPro; IPR023071; Tscrpt_reg_SlyA.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01047; MarR; 1.
DR   PRINTS; PR00598; HTHMARR.
DR   SMART; SM00347; HTH_MARR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS01117; HTH_MARR_1; 1.
DR   PROSITE; PS50995; HTH_MARR_2; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..143
FT                   /note="Transcriptional regulator SlyA"
FT                   /id="PRO_1000070357"
FT   DOMAIN          2..135
FT                   /note="HTH marR-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01819"
FT   DNA_BIND        49..72
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01819"
SQ   SEQUENCE   143 AA;  16240 MW;  462601E99921F502 CRC64;
     MESTLGSDLA RLVRVWRALI DHRLKPLELT QTHWVTLHNI NRLPPEQSQI QLAKAIGIEQ
     PSLVRTLDQL EEKGLITRHT CANDRRAKRI KLTEQSSPII EQVDGVICST RKEILGGISP
     DEIELLSGLI DKLERNIIQL QSK