ID   SLYA_YERPG              Reviewed;         143 AA.
AC   A9QZA1;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Transcriptional regulator SlyA {ECO:0000255|HAMAP-Rule:MF_01819};
GN   Name=slyA {ECO:0000255|HAMAP-Rule:MF_01819};
GN   OrderedLocusNames=YpAngola_A2560;
OS   Yersinia pestis bv. Antiqua (strain Angola).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=349746;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Angola;
RX   PubMed=20061468; DOI=10.1128/jb.01518-09;
RA   Eppinger M., Worsham P.L., Nikolich M.P., Riley D.R., Sebastian Y., Mou S.,
RA   Achtman M., Lindler L.E., Ravel J.;
RT   "Genome sequence of the deep-rooted Yersinia pestis strain Angola reveals
RT   new insights into the evolution and pangenome of the plague bacterium.";
RL   J. Bacteriol. 192:1685-1699(2010).
CC   -!- FUNCTION: Transcription regulator that can specifically activate or
CC       repress expression of target genes. {ECO:0000255|HAMAP-Rule:MF_01819}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01819}.
CC   -!- SIMILARITY: Belongs to the SlyA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01819}.
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DR   EMBL; CP000901; ABX85089.1; -; Genomic_DNA.
DR   RefSeq; WP_002210955.1; NZ_CP009935.1.
DR   AlphaFoldDB; A9QZA1; -.
DR   SMR; A9QZA1; -.
DR   GeneID; 66841281; -.
DR   KEGG; ypg:YpAngola_A2560; -.
DR   PATRIC; fig|349746.12.peg.3584; -.
DR   OMA; CSNDRRA; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_01819; HTH_type_SlyA; 1.
DR   InterPro; IPR000835; HTH_MarR-typ.
DR   InterPro; IPR023187; Tscrpt_reg_MarR-type_CS.
DR   InterPro; IPR023071; Tscrpt_reg_SlyA.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01047; MarR; 1.
DR   PRINTS; PR00598; HTHMARR.
DR   SMART; SM00347; HTH_MARR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS01117; HTH_MARR_1; 1.
DR   PROSITE; PS50995; HTH_MARR_2; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..143
FT                   /note="Transcriptional regulator SlyA"
FT                   /id="PRO_1000188019"
FT   DOMAIN          2..135
FT                   /note="HTH marR-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01819"
FT   DNA_BIND        49..72
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01819"
SQ   SEQUENCE   143 AA;  16170 MW;  62485065D1F5A451 CRC64;
     MESTLGSDLA RLVRVWRALI DHRLKPLELT QTHWVTLYNI NRLPPEQSQI QLAKAIGIEQ
     PSLVRTLDQL EEKGLITRHT CANDRRAKRI KLTEQSSPII EQVDGVICST RKEILGGISS
     DEIAVLSGLI DKLEKNIIQL QTK