BIG1E_ARATH
ID BIG1E_ARATH Reviewed; 321 AA.
AC Q93Z37; Q9LQA5;
DT 14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 25-MAY-2022, entry version 109.
DE RecName: Full=Protein BIG GRAIN 1-like E {ECO:0000305};
GN OrderedLocusNames=At1g69160 {ECO:0000312|EMBL:AEE34889.1};
GN ORFNames=F4N2.12 {ECO:0000312|EMBL:AAF27057.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:AAL25580.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: Involved in auxin transport. Regulator of the auxin signaling
CC pathway. {ECO:0000250|UniProtKB:Q10R09}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q10R09}.
CC -!- SIMILARITY: Belongs to the BIG GRAIN 1 (BG1) plant protein family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF27057.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC008262; AAF27057.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002684; AEE34889.1; -; Genomic_DNA.
DR EMBL; AY058166; AAL25580.1; -; mRNA.
DR EMBL; AY093178; AAM13177.1; -; mRNA.
DR EMBL; BT003390; AAO30053.1; -; mRNA.
DR PIR; E96715; E96715.
DR RefSeq; NP_564952.1; NM_105583.3.
DR AlphaFoldDB; Q93Z37; -.
DR STRING; 3702.AT1G69160.1; -.
DR iPTMnet; Q93Z37; -.
DR PaxDb; Q93Z37; -.
DR PRIDE; Q93Z37; -.
DR ProteomicsDB; 240839; -.
DR EnsemblPlants; AT1G69160.1; AT1G69160.1; AT1G69160.
DR GeneID; 843247; -.
DR Gramene; AT1G69160.1; AT1G69160.1; AT1G69160.
DR KEGG; ath:AT1G69160; -.
DR Araport; AT1G69160; -.
DR TAIR; locus:2033228; AT1G69160.
DR eggNOG; ENOG502RH6J; Eukaryota.
DR HOGENOM; CLU_083143_0_0_1; -.
DR InParanoid; Q93Z37; -.
DR OMA; DHRHTQK; -.
DR OrthoDB; 1101467at2759; -.
DR PhylomeDB; Q93Z37; -.
DR PRO; PR:Q93Z37; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q93Z37; baseline and differential.
DR Genevisible; Q93Z37; AT.
DR GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR GO; GO:0060918; P:auxin transport; ISS:UniProtKB.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0010929; P:positive regulation of auxin mediated signaling pathway; ISS:UniProtKB.
DR InterPro; IPR039621; BG1-like.
DR PANTHER; PTHR33541; PTHR33541; 1.
PE 2: Evidence at transcript level;
KW Auxin signaling pathway; Cell membrane; Membrane; Reference proteome;
KW Transport.
FT CHAIN 1..321
FT /note="Protein BIG GRAIN 1-like E"
FT /id="PRO_0000434448"
FT REGION 134..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..164
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 321 AA; 36327 MW; ED9AE32A927CD590 CRC64;
MSMKGISSAE SDKLSRRISL THKRNSEELD VFEAAVYFGY NEASSGDHGH TQKYGYNAAR
EENPRRWGIL GGGRRISLDL PIRCSEQVYH LQQDHHEKHE VTTIKERLGN VRHKQPSSPG
GKIASFLNSL FHQAGSKKNK SKSKSKTKPT DPEVEEEIPG GGWMRRRRRS SISHFFSSSR
STSTTTTTTA SSSSKSLISS SSSGFRTPPP YLNTPTKNYK QFLNYTSATK QVGEEETKTN
KEYSWLDEKL KVMESLSENQ RIWSDDEDID DDRRIKREGE DDGMESDSSS DLFELQNYEL
SRGGLPVYET TNVANINKTH I
