ID   SM30A_STRPU             Reviewed;         290 AA.
AC   Q26646;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=30 kDa spicule matrix protein alpha;
DE   AltName: Full=SM30-alpha;
DE   Flags: Precursor;
GN   Name=SM30A;
OS   Strongylocentrotus purpuratus (Purple sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae;
OC   Strongylocentrotus.
OX   NCBI_TaxID=7668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Sperm;
RX   PubMed=8051158; DOI=10.1016/s0021-9258(17)32034-3;
RA   Akasaka K., Frudakis T.N., Killian C.E., George N.C., Yamasu K., Khaner O.,
RA   Wilt F.H.;
RT   "Genomic organization of a gene encoding the spicule matrix protein SM30 in
RT   the sea urchin Strongylocentrotus purpuratus.";
RL   J. Biol. Chem. 269:20592-20598(1994).
CC   -!- FUNCTION: Matrix protein of the sea urchin embryo spicule. The function
CC       of the matrix proteins is to direct crystal growth in certain
CC       orientations and inhibit growth in others (By similarity).
CC       {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Accumulates exclusively in mineralized tissues.
CC   -!- DEVELOPMENTAL STAGE: Expressed at the time of spicule formation in the
CC       embryo.
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DR   EMBL; U05962; AAB60620.1; -; Genomic_DNA.
DR   EMBL; U05961; AAB60620.1; JOINED; Genomic_DNA.
DR   PIR; A54855; A54855.
DR   AlphaFoldDB; Q26646; -.
DR   SMR; Q26646; -.
DR   HOGENOM; CLU_960835_0_0_1; -.
DR   InParanoid; Q26646; -.
DR   Proteomes; UP000007110; Unassembled WGS sequence.
DR   GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0030246; F:carbohydrate binding; IBA:GO_Central.
DR   Gene3D; 3.10.100.10; -; 1.
DR   InterPro; IPR001304; C-type_lectin-like.
DR   InterPro; IPR016186; C-type_lectin-like/link_sf.
DR   InterPro; IPR016187; CTDL_fold.
DR   Pfam; PF00059; Lectin_C; 1.
DR   SMART; SM00034; CLECT; 1.
DR   SUPFAM; SSF56436; SSF56436; 1.
DR   PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Reference proteome; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..290
FT                   /note="30 kDa spicule matrix protein alpha"
FT                   /id="PRO_0000017560"
FT   DOMAIN          92..162
FT                   /note="C-type lectin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00040"
FT   CARBOHYD        102
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   290 AA;  31686 MW;  E89B5A5618E724D1 CRC64;
     MRGFVYVLVC VLALASFSRA QLPGGGGPVL PGGGPTIGPV NPDPTRTEVC AKFWVQEGNS
     CYLFDSGAFL RQVAASRPVV VNNENGLFQA AANMYCGQMH PNASLVTVNS LAENNFLYEW
     AVRMMVEPEP VWIGLHAGPM GQWQWYSGEP VTYTNWERMT APMAEPGLGA MIFDADIIAQ
     MFNNQVEITP QWVPEQAIND RHALICEYHP SGMTAAAAAA TNAPTFPPMA TAPPMAATTR
     GPVMFQNNPR NLVNSLTGGR FGGSLLHEIP RRQRMRPSNY RKNPYFGIQP