ID   SM30_STRPU              Reviewed;         290 AA.
AC   P28163;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=30 kDa spicule matrix protein;
DE   Flags: Precursor;
GN   Name=SM30;
OS   Strongylocentrotus purpuratus (Purple sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae;
OC   Strongylocentrotus.
OX   NCBI_TaxID=7668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Embryo;
RX   PubMed=1717322; DOI=10.1016/0012-1606(91)90291-a;
RA   George N.C., Killian C.E., Wilt F.H.;
RT   "Characterization and expression of a gene encoding a 30.6-kDa
RT   Strongylocentrotus purpuratus spicule matrix protein.";
RL   Dev. Biol. 147:334-342(1991).
CC   -!- FUNCTION: Matrix protein of the sea urchin embryo spicule. The function
CC       of the matrix proteins is to direct crystal growth in certain
CC       orientations and inhibit growth in others.
CC   -!- TISSUE SPECIFICITY: Accumulates exclusively in mineralized tissues.
CC   -!- DEVELOPMENTAL STAGE: Is increased at middle to late mesenchyme blastula
CC       stage, level remains high through the 3-day pluteus stage.
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DR   EMBL; M63840; AAA30070.1; -; mRNA.
DR   PIR; A43897; A43897.
DR   RefSeq; NP_999766.1; NM_214601.1.
DR   AlphaFoldDB; P28163; -.
DR   SMR; P28163; -.
DR   EnsemblMetazoa; NM_214601; NP_999766; GeneID_373441.
DR   GeneID; 373441; -.
DR   KEGG; spu:373441; -.
DR   CTD; 373441; -.
DR   HOGENOM; CLU_960835_0_0_1; -.
DR   InParanoid; P28163; -.
DR   PhylomeDB; P28163; -.
DR   Proteomes; UP000007110; Unassembled WGS sequence.
DR   GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0030246; F:carbohydrate binding; IBA:GO_Central.
DR   Gene3D; 3.10.100.10; -; 1.
DR   InterPro; IPR001304; C-type_lectin-like.
DR   InterPro; IPR016186; C-type_lectin-like/link_sf.
DR   InterPro; IPR016187; CTDL_fold.
DR   Pfam; PF00059; Lectin_C; 1.
DR   SMART; SM00034; CLECT; 1.
DR   SUPFAM; SSF56436; SSF56436; 1.
DR   PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Reference proteome; Signal.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000255"
FT   CHAIN           16..290
FT                   /note="30 kDa spicule matrix protein"
FT                   /id="PRO_0000017559"
FT   DOMAIN          92..162
FT                   /note="C-type lectin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00040"
FT   CARBOHYD        102
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   290 AA;  31806 MW;  E1E3E27E40796DF2 CRC64;
     MRGFVYVLVC VLALASFSRA QLPGAGGPVL PGGGPTIGPV NPDPTRTEVC AKFWVQEGNS
     CYLFDSGAFL RQVAASRPVV VNNQDGLFQA AANMYCGQMH PNASLVTVNS LEENNFLYEW
     AVRMMIEPEP VWIGLHAGPT GQWQWYSGEP VTYTNWERMT PPIAEPGLGA MIFDADIIAQ
     MFNNQVEITP QWVPEQAIND RHALICEYHP SGMTAAAAAP TNAPTFPPMT TAPPMAATTR
     GPVMFQNNPR NLVNSLTGGR FGGSLLHEIP RRQRMRPSNY RKNPYFGIQP