ID   SMA2_CANGA              Reviewed;         366 AA.
AC   Q6FKI5;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Spore membrane assembly protein 2;
GN   Name=SMA2; OrderedLocusNames=CAGL0L11286g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in spore and ascus formation. Required for the
CC       efficient assembly of the precursors of the prospore membrane to a
CC       continuous prospore membrane (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Prospore membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SMA2 family. {ECO:0000305}.
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DR   EMBL; CR380958; CAG62233.1; -; Genomic_DNA.
DR   RefSeq; XP_449259.1; XM_449259.1.
DR   AlphaFoldDB; Q6FKI5; -.
DR   STRING; 5478.XP_449259.1; -.
DR   EnsemblFungi; CAG62233; CAG62233; CAGL0L11286g.
DR   GeneID; 2890958; -.
DR   KEGG; cgr:CAGL0L11286g; -.
DR   CGD; CAL0135418; CAGL0L11286g.
DR   VEuPathDB; FungiDB:CAGL0L11286g; -.
DR   eggNOG; ENOG502QW7F; Eukaryota.
DR   HOGENOM; CLU_776604_0_0_1; -.
DR   InParanoid; Q6FKI5; -.
DR   OMA; TIDMGWS; -.
DR   Proteomes; UP000002428; Chromosome L.
DR   GO; GO:0005737; C:cytoplasm; IEA:EnsemblFungi.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005628; C:prospore membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070583; P:spore membrane bending pathway; IEA:EnsemblFungi.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Sporulation; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..366
FT                   /note="Spore membrane assembly protein 2"
FT                   /id="PRO_0000324501"
FT   TOPO_DOM        1..6
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        28..229
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        230..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        251..261
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        262..282
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        283..324
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        325..345
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        346..366
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   366 AA;  41272 MW;  03E2A17FDE010998 CRC64;
     MLIVKRFILW VLLFFMAITQ LLLYLPDFSC SISTGLPLCT PQFNVNIVTG SRTTKDFVSS
     VRQFLRLISY LAIDMGWSKY LADPHIYNEE NLVDTFDTDN LFKINYFGFC KKTSGKTKYC
     VANGDCGMDV LGILVRDVGL QLGRLTQRYE NNTRILGDSL VFTYHLGLSS MRKFLRNDNY
     RNNAFSKLLL ATDDQPYSNT RIKNYAKGVT VAYTLVVVNK IMFYMHLAEI TISAAFVVAV
     LGFGFVLIFG KHHTIMPLLL KGWGSVLMVS STSSYLATIV YLGTLKLLEP TEMLDTQSQV
     AGHVLNNDTH SNNWDLLQTT VGSGFVISCF RYIVQCLMLP LVFIAANRYT KAKDFLPAGT
     EELIKV