ID   SMA5O_HUMAN             Reviewed;          95 AA.
AC   Q9Y6J3;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=SMAD5 antisense gene protein 1;
DE   AltName: Full=10.3 kDa proline-rich protein DAMS;
DE   AltName: Full=SMAD5 antisense RNA 1;
DE   AltName: Full=SMAD5 opposite strand protein;
GN   Name=SMAD5-AS1; Synonyms=DAMS, SMAD5OS;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=10049768; DOI=10.1006/bbrc.1999.0256;
RA   Zavadil J., Svoboda P., Liang H., Kottickal L.V., Nagarajan L.;
RT   "An antisense transcript to SMAD5 expressed in fetal and tumor tissues.";
RL   Biochem. Biophys. Res. Commun. 255:668-672(1999).
CC   -!- TISSUE SPECIFICITY: Expressed in fetal tissues.
CC   -!- MISCELLANEOUS: This protein is coded from a SMAD5 gene antisense
CC       transcript.
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DR   EMBL; AF071111; AAD20804.1; -; mRNA.
DR   AlphaFoldDB; Q9Y6J3; -.
DR   BioMuta; HGNC:30586; -.
DR   PRIDE; Q9Y6J3; -.
DR   GeneCards; SMAD5-AS1; -.
DR   HGNC; HGNC:30586; SMAD5-AS1.
DR   neXtProt; NX_Q9Y6J3; -.
DR   InParanoid; Q9Y6J3; -.
DR   ChiTaRS; SMAD5-AS1; human.
DR   Pharos; Q9Y6J3; Tdark.
DR   PRO; PR:Q9Y6J3; -.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q9Y6J3; protein.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..95
FT                   /note="SMAD5 antisense gene protein 1"
FT                   /id="PRO_0000079777"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          43..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..21
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        49..63
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VARIANT         85
FT                   /note="K -> N (in dbSNP:rs3764941)"
FT                   /id="VAR_020103"
SQ   SEQUENCE   95 AA;  10312 MW;  9D64E9C13984DDC7 CRC64;
     MHKQPKLLPP PATPPPPPQS SSWSGNIVFT IKINIWLRVF SHSSPTGLPK PHSPMPSPPE
     PEHSVGKPAN VQIPQVSSPE FCNQKSVLAT EHAQT