ID   SMAGP_BOVIN             Reviewed;          97 AA.
AC   A4IFL2;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Small cell adhesion glycoprotein;
DE   AltName: Full=Small transmembrane and glycosylated protein;
GN   Name=SMAGP;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal skin;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in epithelial cell-cell contacts. May play a
CC       role in tumor invasiveness and metastasis formation (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q0VAQ4};
CC       Single-pass type III membrane protein {ECO:0000255}. Cytoplasmic
CC       vesicle membrane {ECO:0000250|UniProtKB:Q0VAQ4}; Single-pass type III
CC       membrane protein {ECO:0000255}. Note=Predominantly on lateral parts of
CC       the membrane, at cell-cell epithelial junctions. Detected on
CC       cytoplasmic membranes in undifferentiated tumors.
CC       {ECO:0000250|UniProtKB:Q0VAQ4}.
CC   -!- PTM: O-glycosylated. The O-glycan is modified with sialic acid residues
CC       (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SMAGP family. {ECO:0000305}.
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DR   EMBL; BC134631; AAI34632.1; -; mRNA.
DR   RefSeq; NP_001077262.1; NM_001083793.1.
DR   AlphaFoldDB; A4IFL2; -.
DR   STRING; 9913.ENSBTAP00000002572; -.
DR   PaxDb; A4IFL2; -.
DR   PRIDE; A4IFL2; -.
DR   Ensembl; ENSBTAT00000002572; ENSBTAP00000002572; ENSBTAG00000001983.
DR   GeneID; 787004; -.
DR   KEGG; bta:787004; -.
DR   CTD; 57228; -.
DR   VEuPathDB; HostDB:ENSBTAG00000001983; -.
DR   VGNC; VGNC:34982; SMAGP.
DR   eggNOG; ENOG502S7EH; Eukaryota.
DR   GeneTree; ENSGT00390000010077; -.
DR   HOGENOM; CLU_175196_0_0_1; -.
DR   InParanoid; A4IFL2; -.
DR   OMA; AVQMEDD; -.
DR   OrthoDB; 1609419at2759; -.
DR   Proteomes; UP000009136; Chromosome 5.
DR   Bgee; ENSBTAG00000001983; Expressed in abomasum and 104 other tissues.
DR   ExpressionAtlas; A4IFL2; baseline and differential.
DR   GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR043243; SMAGP.
DR   PANTHER; PTHR47394; PTHR47394; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Cytoplasmic vesicle; Glycoprotein; Membrane;
KW   Reference proteome; Sialic acid; Transmembrane; Transmembrane helix.
FT   CHAIN           1..97
FT                   /note="Small cell adhesion glycoprotein"
FT                   /id="PRO_0000328794"
FT   TOPO_DOM        1..36
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        37..57
FT                   /note="Helical; Signal-anchor for type III membrane
FT                   protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        58..97
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3
FT                   /note="O-linked (GalNAc...) serine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        6
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        7
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        17
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        18
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        23
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   97 AA;  10565 MW;  1D17AA00C510FBA9 CRC64;
     MTSFPTTPPP AEELMATTIL QATEALSPEA EASTALIAVV ITVVFLTLLS VVILIFFYLY
     KNKGSYVTYE PADGEPGAVV LMENDSAKGR EKEEYFI