ID   SMAKA_BOVIN             Reviewed;          95 AA.
AC   Q3SZY8;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Small membrane A-kinase anchor protein;
DE            Short=Small membrane AKAP;
DE            Short=smAKAP;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Binds to type I regulatory subunits of protein kinase A (PKA-
CC       RI) and may anchor/target them to the plasma membrane. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with PKA type I regulatory subunits PRKAR1A and
CC       PRKAR1B. Also binds to type II regulatory subunits, but at a tenfold
CC       lower affinity (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}.
CC   -!- PTM: May be palmitoylated at Cys-3. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the small membrane AKAP family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC102650; AAI02651.1; -; mRNA.
DR   RefSeq; NP_001070459.1; NM_001076991.2.
DR   RefSeq; XP_010800113.1; XM_010801811.2.
DR   RefSeq; XP_010800114.1; XM_010801812.2.
DR   AlphaFoldDB; Q3SZY8; -.
DR   SMR; Q3SZY8; -.
DR   STRING; 9913.ENSBTAP00000038453; -.
DR   PaxDb; Q3SZY8; -.
DR   Ensembl; ENSBTAT00000038641; ENSBTAP00000038453; ENSBTAG00000026994.
DR   GeneID; 767914; -.
DR   KEGG; bta:767914; -.
DR   CTD; 118838326; -.
DR   VEuPathDB; HostDB:ENSBTAG00000026994; -.
DR   VGNC; VGNC:52705; C2H2orf88.
DR   eggNOG; ENOG502S8S1; Eukaryota.
DR   GeneTree; ENSGT00390000011537; -.
DR   HOGENOM; CLU_187810_0_0_1; -.
DR   InParanoid; Q3SZY8; -.
DR   OMA; CIKSKDA; -.
DR   OrthoDB; 1536209at2759; -.
DR   TreeFam; TF338355; -.
DR   Proteomes; UP000009136; Chromosome 2.
DR   Bgee; ENSBTAG00000026994; Expressed in semen and 89 other tissues.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0034237; F:protein kinase A regulatory subunit binding; IEA:InterPro.
DR   InterPro; IPR027969; Small_membr_AKAP.
DR   PANTHER; PTHR36471; PTHR36471; 1.
DR   Pfam; PF15127; SmAKAP; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Myristate; Palmitate; Phosphoprotein;
KW   Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000255"
FT   CHAIN           2..95
FT                   /note="Small membrane A-kinase anchor protein"
FT                   /id="PRO_0000348429"
FT   REGION          56..74
FT                   /note="PKA-RI-binding"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         40
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9CPS8"
FT   MOD_RES         92
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BSF0"
FT   LIPID           2
FT                   /note="N-myristoyl glycine"
FT                   /evidence="ECO:0000255"
FT   LIPID           3
FT                   /note="S-palmitoyl cysteine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   95 AA;  10969 MW;  1AB45BB1678F1C50 CRC64;
     MGCMKSKQTF PFPTTLESEK RHVSEENFMP EEKFLPRIPS LVNVKEEVKE PPGPQIVVFE
     FAQHLSQEIL SDALQQWAGN NLKYYDIPYI ESEGP