SMAX1_ARATH
ID SMAX1_ARATH Reviewed; 990 AA.
AC Q9FHH2;
DT 16-MAR-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Protein SUPPRESSOR OF MAX2 1 {ECO:0000303|PubMed:23893171};
DE Short=AtSMXL1 {ECO:0000303|PubMed:23893171};
GN Name=SMAX1 {ECO:0000303|PubMed:23893171};
GN OrderedLocusNames=At5g57710 {ECO:0000312|Araport:AT5G57710};
GN ORFNames=MRI1.7 {ECO:0000312|EMBL:BAB09589.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10470850; DOI=10.1093/dnares/6.3.183;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Kotani H.,
RA Miyajima N., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IX. Sequence
RT features of the regions of 1,011,550 bp covered by seventeen P1 and TAC
RT clones.";
RL DNA Res. 6:183-195(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP INDUCTION BY KARRIKINS.
RX PubMed=20351290; DOI=10.1073/pnas.0911635107;
RA Nelson D.C., Flematti G.R., Riseborough J.A., Ghisalberti E.L., Dixon K.W.,
RA Smith S.M.;
RT "Karrikins enhance light responses during germination and seedling
RT development in Arabidopsis thaliana.";
RL Proc. Natl. Acad. Sci. U.S.A. 107:7095-7100(2010).
RN [4]
RP FUNCTION, INDUCTION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, DISRUPTION
RP PHENOTYPE, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=23893171; DOI=10.1104/pp.113.221259;
RA Stanga J.P., Smith S.M., Briggs W.R., Nelson D.C.;
RT "SUPPRESSOR OF MORE AXILLARY GROWTH2 1 controls seed germination and
RT seedling development in Arabidopsis.";
RL Plant Physiol. 163:318-330(2013).
RN [5]
RP REVIEW.
RX PubMed=25179782; DOI=10.1016/j.pbi.2014.08.001;
RA Bennett T., Leyser O.;
RT "Strigolactone signalling: standing on the shoulders of DWARFs.";
RL Curr. Opin. Plant Biol. 22:7-13(2014).
RN [6]
RP FUNCTION, DISRUPTION PHENOTYPE, TISSUE SPECIFICITY, INTERACTION WITH TPL;
RP TPR1; TPR2 AND TPR4, AND EAR MOTIF.
RX PubMed=26546447; DOI=10.1105/tpc.15.00562;
RA Soundappan I., Bennett T., Morffy N., Liang Y., Stanga J.P., Abbas A.,
RA Leyser O., Nelson D.C.;
RT "SMAX1-LIKE/D53 family members enable distinct MAX2-dependent responses to
RT strigolactones and karrikins in Arabidopsis.";
RL Plant Cell 27:3143-3159(2015).
RN [7]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=26754282; DOI=10.1007/s00425-015-2458-2;
RA Stanga J.P., Morffy N., Nelson D.C.;
RT "Functional redundancy in the control of seedling growth by the karrikin
RT signaling pathway.";
RL Planta 243:1397-1406(2016).
CC -!- FUNCTION: Probable component of a transcriptional corepressor complex
CC that acts downstream of MAX2 to negatively regulate
CC karrikins/strigolactone responses (PubMed:23893171, PubMed:26546447).
CC Probable target of MAX2 during germination and seedling
CC photomorphogenesis (PubMed:26546447). Acts probably specifically in the
CC karrikin pathway (PubMed:26754282). {ECO:0000269|PubMed:26546447,
CC ECO:0000269|PubMed:26754282, ECO:0000305|PubMed:23893171}.
CC -!- SUBUNIT: Interacts probably with TPL/TPR in an EAR-motif dependent
CC manner. Interacts with TPL, TPR1, TPR2 and TPR4.
CC {ECO:0000269|PubMed:26546447}.
CC -!- TISSUE SPECIFICITY: Highly expressed in dry seeds. Expressed in
CC seedlings, rosette leaves and senescing leaves. Detected in roots and
CC axillary shoots (PubMed:23893171). Expressed in the primary rosette
CC buds and expanding leaves of adult rosettes, the vasculature of the
CC hypocotyls, cotyledons, and mature roots, in the midvein and petioles
CC of young leaves, the young leaf periphery, stomata, and the root caps
CC (PubMed:26546447). {ECO:0000269|PubMed:23893171,
CC ECO:0000269|PubMed:26546447}.
CC -!- DEVELOPMENTAL STAGE: Peak of expression in seeds during maturation.
CC {ECO:0000269|PubMed:23893171}.
CC -!- INDUCTION: Up-regulated by karrikins treatments (PubMed:20351290).
CC Under MAX2-dependent negative feedback regulation (PubMed:23893171).
CC {ECO:0000269|PubMed:20351290, ECO:0000269|PubMed:23893171}.
CC -!- DOMAIN: Contains 1 EAR motif required for the interaction with TPR2.
CC {ECO:0000269|PubMed:26546447}.
CC -!- DISRUPTION PHENOTYPE: Low seed dormancy and short hypocotyls
CC (PubMed:23893171). Suppresses max2 phenotypes associated with karrikin-
CC KAI2-regulated growth (PubMed:26546447). Smax1 and smxl2 double mutants
CC have substential reduction in hypocotyl elongation (PubMed:26754282).
CC {ECO:0000269|PubMed:23893171, ECO:0000269|PubMed:26546447,
CC ECO:0000269|PubMed:26754282}.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family. {ECO:0000305}.
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DR EMBL; AB018118; BAB09589.1; -; Genomic_DNA.
DR EMBL; CP002688; AED96941.1; -; Genomic_DNA.
DR RefSeq; NP_200579.1; NM_125154.4.
DR AlphaFoldDB; Q9FHH2; -.
DR STRING; 3702.AT5G57710.1; -.
DR PaxDb; Q9FHH2; -.
DR PRIDE; Q9FHH2; -.
DR ProteomicsDB; 232565; -.
DR EnsemblPlants; AT5G57710.1; AT5G57710.1; AT5G57710.
DR GeneID; 835878; -.
DR Gramene; AT5G57710.1; AT5G57710.1; AT5G57710.
DR KEGG; ath:AT5G57710; -.
DR Araport; AT5G57710; -.
DR TAIR; locus:2172585; AT5G57710.
DR eggNOG; KOG1051; Eukaryota.
DR HOGENOM; CLU_006575_0_2_1; -.
DR InParanoid; Q9FHH2; -.
DR OMA; RTSCCPQ; -.
DR OrthoDB; 173851at2759; -.
DR PhylomeDB; Q9FHH2; -.
DR PRO; PR:Q9FHH2; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FHH2; baseline and differential.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0080167; P:response to karrikin; IMP:TAIR.
DR GO; GO:1902347; P:response to strigolactone; IMP:TAIR.
DR GO; GO:0009845; P:seed germination; IMP:TAIR.
DR GO; GO:0090351; P:seedling development; IMP:TAIR.
DR Gene3D; 1.10.1780.10; -; 1.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF07724; AAA_2; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF81923; SSF81923; 1.
DR PROSITE; PS51903; CLP_R; 1.
PE 1: Evidence at protein level;
KW Hydrolase; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..990
FT /note="Protein SUPPRESSOR OF MAX2 1"
FT /id="PRO_0000435710"
FT DOMAIN 8..167
FT /note="Clp R"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT REGION 12..83
FT /note="Repeat 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT REGION 96..167
FT /note="Repeat 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01251"
FT REGION 818..855
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 828..832
FT /note="EAR"
FT /evidence="ECO:0000305|PubMed:26546447"
SQ SEQUENCE 990 AA; 108710 MW; A0BA396F566466CB CRC64;
MRAGLSTIQQ TLTPEAATVL NQSIAEAARR NHGQTTPLHV AATLLASPAG FLRRACIRSH
PNSSHPLQCR ALELCFSVAL ERLPTATTTP GNDPPISNAL MAALKRAQAH QRRGCPEQQQ
QPLLAVKVEL EQLIISILDD PSVSRVMREA SFSSPAVKAT IEQSLNNSVT PTPIPSVSSV
GLNFRPGGGG PMTRNSYLNP RLQQNASSVQ SGVSKNDDVE RVMDILGRAK KKNPVLVGDS
EPGRVIREIL KKIEVGEVGN LAVKNSKVVS LEEISSDKAL RIKELDGLLQ TRLKNSDPIG
GGGVILDLGD LKWLVEQPSS TQPPATVAVE IGRTAVVELR RLLEKFEGRL WFIGTATCET
YLRCQVYHPS VETDWDLQAV SVAAKAPASG VFPRLANNLE SFTPLKSFVP ANRTLKCCPQ
CLQSYERELA EIDSVSSPEV KSEVAQPKQL PQWLLKAKPV DRLPQAKIEE VQKKWNDACV
RLHPSFHNKN ERIVPIPVPI TLTTSPYSPN MLLRQPLQPK LQPNRELRER VHLKPMSPLV
AEQAKKKSPP GSPVQTDLVL GRAEDSEKAG DVQVRDFLGC ISSESVQNNN NISVLQKENL
GNSLDIDLFK KLLKGMTEKV WWQNDAAAAV AATVSQCKLG NGKRRGVLSK GDVWLLFSGP
DRVGKRKMVS ALSSLVYGTN PIMIQLGSRQ DAGDGNSSFR GKTALDKIAE TVKRSPFSVI
LLEDIDEADM LVRGSIKQAM DRGRIRDSHG REISLGNVIF VMTASWHFAG TKTSFLDNEA
KLRDLASESW RLRLCMREKF GKRRASWLCS DEERLTKPKK EHGSGLSFDL NQAADTDDGS
HNTSDLTTDN DQDEQGFSGK LSLQCVPFAF HDMVSRVDDA VAFRAVDFAA VRRRITETLS
ERFETIIGES LSVEVEEEAL QRILSGVWLG QTELEEWIEK AIVPVLSQLK ARVSSSGTYG
DCTVARLELD EDSGERNAGD LLPTTITLAV
