ID   SMCO4_AEDAE             Reviewed;          60 AA.
AC   Q0IFA9;
DT   03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Single-pass membrane and coiled-coil domain-containing protein 4 homolog;
GN   ORFNames=AAEL005900;
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LVPib12;
RX   PubMed=17510324; DOI=10.1126/science.1138878;
RA   Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA   Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA   Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA   Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA   Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA   Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA   El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA   Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA   Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA   Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA   Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA   Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA   Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA   Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA   Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA   Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA   Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT   "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL   Science 316:1718-1723(2007).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SMCO4 family. {ECO:0000305}.
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DR   EMBL; CH477364; EAT42585.1; -; Genomic_DNA.
DR   RefSeq; XP_001651591.1; XM_001651541.1.
DR   AlphaFoldDB; Q0IFA9; -.
DR   SMR; Q0IFA9; -.
DR   STRING; 7159.AAEL005900-PA; -.
DR   GeneID; 5567161; -.
DR   KEGG; aag:5567161; -.
DR   VEuPathDB; VectorBase:AAEL005900; -.
DR   eggNOG; ENOG502S7F4; Eukaryota.
DR   HOGENOM; CLU_209950_1_0_1; -.
DR   InParanoid; Q0IFA9; -.
DR   OMA; PRKETWK; -.
DR   OrthoDB; 1641948at2759; -.
DR   PhylomeDB; Q0IFA9; -.
DR   Proteomes; UP000008820; Chromosome 3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR027960; DUF4519.
DR   PANTHER; PTHR34644; PTHR34644; 1.
DR   Pfam; PF15012; DUF4519; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..60
FT                   /note="Single-pass membrane and coiled-coil domain-
FT                   containing protein 4 homolog"
FT                   /id="PRO_0000365551"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          10..33
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   60 AA;  7250 MW;  E5E89E12F31D3D78 CRC64;
     MRKLRGGQTK ETRKQKQERR EENLKIQQQL KTIVLPICGV FLMCIVVYVF LKTRPRFEEL