ID   SMC_BURP1               Reviewed;        1170 AA.
AC   Q3JR19;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   31-MAY-2011, sequence version 2.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Chromosome partition protein Smc {ECO:0000255|HAMAP-Rule:MF_01894};
GN   Name=smc {ECO:0000255|HAMAP-Rule:MF_01894};
GN   OrderedLocusNames=BURPS1710b_2592;
OS   Burkholderia pseudomallei (strain 1710b).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=320372;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1710b;
RX   PubMed=20333227; DOI=10.1093/gbe/evq003;
RA   Losada L., Ronning C.M., DeShazer D., Woods D., Fedorova N., Kim H.S.,
RA   Shabalina S.A., Pearson T.R., Brinkac L., Tan P., Nandi T., Crabtree J.,
RA   Badger J., Beckstrom-Sternberg S., Saqib M., Schutzer S.E., Keim P.,
RA   Nierman W.C.;
RT   "Continuing evolution of Burkholderia mallei through genome reduction and
RT   large-scale rearrangements.";
RL   Genome Biol. Evol. 2:102-116(2010).
CC   -!- FUNCTION: Required for chromosome condensation and partitioning.
CC       {ECO:0000255|HAMAP-Rule:MF_01894}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01894}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01894}.
CC   -!- DOMAIN: Contains large globular domains required for ATP hydrolysis at
CC       each terminus and a third globular domain forming a flexible SMC hinge
CC       near the middle of the molecule. These domains are separated by coiled-
CC       coil structures. {ECO:0000255|HAMAP-Rule:MF_01894}.
CC   -!- SIMILARITY: Belongs to the SMC family. {ECO:0000255|HAMAP-
CC       Rule:MF_01894}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABA47647.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; CP000124; ABA47647.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_004527298.1; NC_007434.1.
DR   AlphaFoldDB; Q3JR19; -.
DR   SMR; Q3JR19; -.
DR   PRIDE; Q3JR19; -.
DR   EnsemblBacteria; ABA47647; ABA47647; BURPS1710b_2592.
DR   KEGG; bpm:BURPS1710b_2592; -.
DR   HOGENOM; CLU_001042_2_2_4; -.
DR   OrthoDB; 1149850at2; -.
DR   Proteomes; UP000002700; Chromosome I.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 2.
DR   HAMAP; MF_01894; Smc_prok; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   InterPro; IPR024704; SMC.
DR   InterPro; IPR010935; SMC_hinge.
DR   InterPro; IPR036277; SMC_hinge_sf.
DR   InterPro; IPR011890; SMC_prok.
DR   Pfam; PF06470; SMC_hinge; 1.
DR   Pfam; PF02463; SMC_N; 1.
DR   PIRSF; PIRSF005719; SMC; 1.
DR   SMART; SM00968; SMC_hinge; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF75553; SSF75553; 1.
DR   TIGRFAMs; TIGR02168; SMC_prok_B; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coiled coil; Cytoplasm; DNA-binding; Nucleotide-binding.
FT   CHAIN           1..1170
FT                   /note="Chromosome partition protein Smc"
FT                   /id="PRO_0000409265"
FT   DOMAIN          520..623
FT                   /note="SMC hinge"
FT   COILED          169..215
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
FT   COILED          245..365
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
FT   COILED          401..508
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
FT   COILED          664..944
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
FT   COILED          983..1020
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
FT   BINDING         32..39
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
SQ   SEQUENCE   1170 AA;  129041 MW;  D2A219E3AEF0B32A CRC64;
     MRLSSIKLAG FKSFVDPTHF QVPGQLVGVV GPNGCGKSNI IDAVRWVLGE SRASELRGES
     MQDVIFNGST TRKPGSRASV ELIFDNSDGR AAGQWGQYGE IAVKRVLTRD GTSSYYINNL
     PARRRDIQDI FLGTGLGPRA YAIIGQGMIA RIIEAKPEEL RVFLEEAAGV SKYKERRRET
     ENRLHDTREN LTRVEDIVRE LGANLEKLEA QAVVATKYKE LVADGEEKQR LLWLLRKNEA
     AAEQDRQRRA IGDAQIELDA QTAKLREVEA QLETLRVAHY SASDAMQGAQ GALYEANAEV
     SRLEAQIKFI VESRNRVQAQ IAALVAQQEQ WRAQADKAQG DLEVAEEARA VADEKAAIAE
     DDAAAKHDAL PALEARWRDA QTGLNDERGR IAQTEQALKL EAAHQRNADQ QLQQLQQRHE
     RLKVEAGGLD APDEAQLEEL RMQLAEHEAM LAEAQARLAD AQEALPRLDA QRRAAHERVQ
     AESAQIHQLE ARLAALKQLQ ENVQTQGKIQ PWLDKHELGA LPRLWKKLHV EAGWETALEA
     VLRERLAALE VSNLDWVKAF ATDAPPAKLA FYAPPAAGEP LAAPGALRPL LPLVRIDDAG
     LRAVLNDWLG TVFVADDLAQ ALAARMQLPQ GGAFVVKAGH VVTRSGVQLY AADSEQAGML
     ARAQEIENLT RQVRAQALLS DEAKAAAIRA EAAHTQASQA LTEVRAQAER ATQRVHALQM
     DVLKLTQAHE RYTQRSTQIR EELEEIGAQI EEQRALRAES EANFERHDAE LAELQARFED
     NQLAFESLDE TLTNARQEAR ERERAATDAR FAARQSANRI DELKRSIQVA HEQAERVAAS
     LEDARAELET INEQTAHTGL QDALEVRAAK EQALGAARAE LDDLTAKLRA ADEARLAAER
     SLQPLRDRIT ELQLKEQAAR MTGEQFAEQL ATAEVDEAAL KEKLMPDMKP SYLQGEVTRI
     NNAINALGPV NMAALDELAA ASERKVFLDA QSADLTNAIE TLEDAIRKID QETRALLQAT
     FDEVNRHFSD LFPRLFGGGQ AKLIMTGDEI LDAGVQVMAQ PPGKKNATIH LLSGGEKALT
     ATALVFAMFQ LNPAPFCLLD EVDAPLDDAN TERFANLVRA MSDKTQFLFI SHNKIAMEMA
     QQLIGVTMQE QGVSRIVAVD METAAGFAQN