ID   SMC_COXBU               Reviewed;        1169 AA.
AC   Q81ZL2; Q7C3I8;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Chromosome partition protein Smc {ECO:0000255|HAMAP-Rule:MF_01894};
GN   Name=smc {ECO:0000255|HAMAP-Rule:MF_01894}; OrderedLocusNames=CBU_0540;
OS   Coxiella burnetii (strain RSA 493 / Nine Mile phase I).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC   Coxiella.
OX   NCBI_TaxID=227377;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=14660695; DOI=10.1093/molbev/msh023;
RA   Cobbe N., Heck M.M.S.;
RT   "The evolution of SMC proteins: phylogenetic analysis and structural
RT   implications.";
RL   Mol. Biol. Evol. 21:332-347(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RSA 493 / Nine Mile phase I;
RX   PubMed=12704232; DOI=10.1073/pnas.0931379100;
RA   Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C.,
RA   Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T.,
RA   Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M.,
RA   Lee K.H., Carty H.A., Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E.,
RA   Fraser C.M., Heidelberg J.F.;
RT   "Complete genome sequence of the Q-fever pathogen, Coxiella burnetii.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
CC   -!- FUNCTION: Required for chromosome condensation and partitioning.
CC       {ECO:0000255|HAMAP-Rule:MF_01894}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01894}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01894}.
CC   -!- DOMAIN: Contains large globular domains required for ATP hydrolysis at
CC       each terminus and a third globular domain forming a flexible hinge near
CC       the middle of the molecule. These domains are separated by coiled-coil
CC       structures. {ECO:0000255|HAMAP-Rule:MF_01894}.
CC   -!- SIMILARITY: Belongs to the SMC family. {ECO:0000255|HAMAP-
CC       Rule:MF_01894}.
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DR   EMBL; AE016828; AAO90086.1; -; Genomic_DNA.
DR   EMBL; AJ543641; CAD66594.1; -; Genomic_DNA.
DR   RefSeq; NP_819572.1; NC_002971.3.
DR   RefSeq; WP_010957646.1; NC_002971.4.
DR   AlphaFoldDB; Q81ZL2; -.
DR   SMR; Q81ZL2; -.
DR   STRING; 227377.CBU_0540; -.
DR   EnsemblBacteria; AAO90086; AAO90086; CBU_0540.
DR   GeneID; 1208425; -.
DR   KEGG; cbu:CBU_0540; -.
DR   PATRIC; fig|227377.7.peg.533; -.
DR   eggNOG; COG1196; Bacteria.
DR   HOGENOM; CLU_001042_2_2_6; -.
DR   OMA; HNKIAME; -.
DR   Proteomes; UP000002671; Chromosome.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 2.
DR   HAMAP; MF_01894; Smc_prok; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   InterPro; IPR024704; SMC.
DR   InterPro; IPR010935; SMC_hinge.
DR   InterPro; IPR036277; SMC_hinge_sf.
DR   InterPro; IPR011890; SMC_prok.
DR   Pfam; PF02463; SMC_N; 1.
DR   PIRSF; PIRSF005719; SMC; 1.
DR   SMART; SM00968; SMC_hinge; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF75553; SSF75553; 1.
DR   TIGRFAMs; TIGR02168; SMC_prok_B; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coiled coil; Cytoplasm; DNA-binding; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..1169
FT                   /note="Chromosome partition protein Smc"
FT                   /id="PRO_0000409269"
FT   COILED          170..507
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
FT   COILED          659..1030
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
FT   BINDING         32..39
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
SQ   SEQUENCE   1169 AA;  133551 MW;  A954FBE459169FFF CRC64;
     MYLKTIKLAG FKSFVDPTLI PIRGSMNAIV GPNGCGKSNV VDAVRWVIGE TSAKQLRGQS
     MSDVIFNGTT SRKPVGKASI ELHFDNSEGR IGGEYAKYGE IAIRREVERD GQSNYFINGA
     HVRRRDVVDV FLGTGLGPRS YAIVEQGMIS NLIEAKPEEL RVYIEEAAGI SKYKERRRET
     ESRMRHTQEN LDRVNDIAEE LAKQLRHLKR QANAAERYKA YKQEERALGA QFKVLQWKAL
     DHKLSEHDQA INQKNTRREE KQSEQHRIET EIEKMREQLT DVNEKHNAVQ KRYYGLGADI
     ARLEQRIKDT QEKIHQWQSE LEENENVWEE LQNNTAECEA QITELETELE HLKPRSSDIH
     SAAAEASKEL AQAESNMARW QEAWEAFQAE TSQTMSQLEV MRTKREHCER QLTDLEKSKQ
     QLQQNLKQLQ LDQLLNEIAP LSSQSELLNA ELSDSQSKLQ SLAETIASRR DANQTTREEL
     QTQRRELQAL EARAASLEAL QKAALGESDG KISEWLSSQQ LKENPRLGQK LVVNPGWEIA
     VETVLSGFFD AVCVDAALPF LTDLTTVSEG RVTLVEKKSV SASAFDKAPT LASQVKSEWP
     FQQWLAGIYI ADTLDQAKQL QSSLQENESV ITKEGLWLGP HWARISKLQD APQSGFLLRE
     QQLKQLKANI LGQQKKCDEQ EALLKSGEQQ LNQLETDRDT LLQTYQKLNA EATTVQSALS
     TKQAQLDNAQ QQQTRLKIGL NECEQQIEQC QQQLTLIKNK ASSLDDSQGL LATRREEMIR
     ERDHYRTQLI ELREKAHQKR KEADELEIRL ASNEDQLSLL RQTVARDQRQ LKQLTERREM
     LSQYLSEGDK PLEELNEKLQ TQLEQRLILE TELREVEKEL EEANQLLRHL EEKRVSTQKA
     LNEAQAQLEE LRMQRQTVSV RQTTIKEQLS ENDFDLEQVM AELPEEATIE SWQEKLDQLV
     ERIQRMGPIN LAAIEEYESV NERKNYLDKQ HADLTEALEI LKNAIHKIDR ETRAKFQETY
     DQVNQQFQSL FPRIFGGGRA TLEMTDTDLL TAGVIVRAQP PGKRNVTIHM LSGGEKALTA
     VALVFSLFQL NPAPFCILDE VDAPLDDINV GRFCQLVKEM SKEVQFLVIS HNKVTIEMAD
     YLMGVTMQEP GVSRIVSVNM QEAIGLVEA