SMC_KORVE
ID SMC_KORVE Reviewed; 1308 AA.
AC Q1INB1;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 13-JUN-2006, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Chromosome partition protein Smc {ECO:0000255|HAMAP-Rule:MF_01894};
GN Name=smc {ECO:0000255|HAMAP-Rule:MF_01894}; OrderedLocusNames=Acid345_2638;
OS Koribacter versatilis (strain Ellin345).
OC Bacteria; Acidobacteria; Acidobacteriales; Acidobacteriaceae;
OC Candidatus Koribacter.
OX NCBI_TaxID=204669;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ellin345;
RX PubMed=19201974; DOI=10.1128/aem.02294-08;
RA Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M.,
RA Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B.,
RA Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C.,
RA Davidsen T.M., DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S.,
RA Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P.,
RA Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q.,
RA Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R.,
RA Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R.;
RT "Three genomes from the phylum Acidobacteria provide insight into the
RT lifestyles of these microorganisms in soils.";
RL Appl. Environ. Microbiol. 75:2046-2056(2009).
CC -!- FUNCTION: Required for chromosome condensation and partitioning.
CC {ECO:0000255|HAMAP-Rule:MF_01894}.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01894}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01894}.
CC -!- DOMAIN: Contains large globular domains required for ATP hydrolysis at
CC each terminus and a third globular domain forming a flexible SMC hinge
CC near the middle of the molecule. These domains are separated by coiled-
CC coil structures. {ECO:0000255|HAMAP-Rule:MF_01894}.
CC -!- SIMILARITY: Belongs to the SMC family. {ECO:0000255|HAMAP-
CC Rule:MF_01894}.
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DR EMBL; CP000360; ABF41639.1; -; Genomic_DNA.
DR RefSeq; WP_011523440.1; NC_008009.1.
DR AlphaFoldDB; Q1INB1; -.
DR SMR; Q1INB1; -.
DR STRING; 204669.Acid345_2638; -.
DR PRIDE; Q1INB1; -.
DR EnsemblBacteria; ABF41639; ABF41639; Acid345_2638.
DR KEGG; aba:Acid345_2638; -.
DR eggNOG; COG1196; Bacteria.
DR HOGENOM; CLU_001042_2_2_0; -.
DR OMA; HNKIAME; -.
DR OrthoDB; 1149850at2; -.
DR Proteomes; UP000002432; Chromosome.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR Gene3D; 3.40.50.300; -; 3.
DR HAMAP; MF_01894; Smc_prok; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR InterPro; IPR011890; SMC_prok.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 2.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF75553; SSF75553; 1.
DR TIGRFAMs; TIGR02168; SMC_prok_B; 1.
PE 3: Inferred from homology;
KW ATP-binding; Coiled coil; Cytoplasm; DNA-binding; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..1308
FT /note="Chromosome partition protein Smc"
FT /id="PRO_0000409261"
FT DOMAIN 637..757
FT /note="SMC hinge"
FT REGION 115..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 278..600
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
FT COILED 791..1046
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
FT COILED 1110..1148
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
FT COMPBIAS 130..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 34..41
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
SQ SEQUENCE 1308 AA; 145208 MW; 4FCBD73C568E55CD CRC64;
MLKLKKLQLL GFKSFCDRTE LKFPGDGIAA IVGPNGCGKS NIADAISWVL GEQSAKSLRG
IHMQDVIFAG TRDRKPTGMA EVSLTLIDPE QYEGKIVEPE IEIRDEMPDD WDEAAAREAS
MEEVDEYTAE VQPGTNTEAE ATEQQAAPSE GAAPTTEATA PSTENEAAPS EVAEGQPSDA
QAAVINPNAV VLKIRRRKFN TNRFKKGEIC VTRRLFRSGD SEYLLNGKLS RLRDVHDIFM
GTGLGPESYA IIEQGRIGQI LSSKPTDRRA IIEEAAGITK YKTKKRLAEA RLEDAKSNLA
RVNDIFDEVT RQMNSLKRQA AKAERYAKLR DEMREKLRVV LASKFALIDA EIAGLEAELT
TVTEEIATRT DAVQQMDNEH GERVQRGYAI DAEAKQNRES LNNVSREMDR AAQRRRTNEE
RCAELVARSA GAEAEIQNTT EQLGRLEEEL ATNRQVLESA AADVAVAQSD LQTKQQEASA
AAANLMNVER EQEQRRSQIF QAVNAASNVR NRITQAEERI ANLDREHGRV TGELSSATLQ
LESFGGQRGQ LGLEFESANT RVNALSSEIT DARGSLQQKR QEEIEAKRHV DTLRAEYATL
LGKKGSLESV INEHGYSTES VKRLFQSGGL REGNTPAGVL ADFLEVEDKY EHVVEDFLRD
ELNYVVVKSW GAADEGLRLL KGDVDGRATF LVHPSDSQAK FSFVLDESMR LPFTPDRVTP
MKNCIRVLNG FGKSLEVVLP KLGNGYIVPD PAIGRELALE NPDAFFLSQS GECFHNVTVT
GGKQRSQGPL SLKRELRDVM RCIDDVERSL RDGEARVLML GKEIAELTSL LQRLEDEKRE
GEKQAMTSGH TLRQLENEMA RVRDRHATYE RELQRVSNEK SERENAIGGL RMELEAAEAR
HQELEAAMNA ATQSLDELRT ARDNASHAAS EARAQAAALE ERHRAAASSL QRIESMVQEV
SARIGKLKGQ VESAAAEKQQ RESENETIAE QLVTWTAERE AAEARDRELQ TESEQVRARI
AEIEEELKTA RQALDAARDR RGELHASVAR LQSDGEHMAE TCVQELSVTR PDLMAIEELP
RLTGDELAVA DTEQKDMRTK LENMGPVNMM ALEEYKETAQ RHEFLETQRK DLLDSIENTQ
NTIKEIDQIT KVKFDEAFAA INENFGKAFK KLFGGGQGFM KLTDELNSSD SGIDVIASPP
GKKLQNVLLL SGGEKTLTAF SLLVGIFQYA PSPFCILDEV DAPLDETNVA RFNELVKEMS
MQTQFILITH SKRTMATAPV MYGVTMQEPG VSKIVSVRFG EEAARATA
