SMC_LACPL
ID SMC_LACPL Reviewed; 1185 AA.
AC Q88WJ9; F9UP04;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Chromosome partition protein Smc {ECO:0000255|HAMAP-Rule:MF_01894};
GN Name=smc {ECO:0000255|HAMAP-Rule:MF_01894}; OrderedLocusNames=lp_1632;
OS Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
OS (Lactobacillus plantarum).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactiplantibacillus.
OX NCBI_TaxID=220668;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1;
RX PubMed=12566566; DOI=10.1073/pnas.0337704100;
RA Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., Kuipers O.P.,
RA Leer R., Tarchini R., Peters S.A., Sandbrink H.M., Fiers M.W.E.J.,
RA Stiekema W., Klein Lankhorst R.M., Bron P.A., Hoffer S.M.,
RA Nierop Groot M.N., Kerkhoven R., De Vries M., Ursing B., De Vos W.M.,
RA Siezen R.J.;
RT "Complete genome sequence of Lactobacillus plantarum WCFS1.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1;
RX PubMed=22156394; DOI=10.1128/jb.06275-11;
RA Siezen R.J., Francke C., Renckens B., Boekhorst J., Wels M.,
RA Kleerebezem M., van Hijum S.A.;
RT "Complete resequencing and reannotation of the Lactobacillus plantarum
RT WCFS1 genome.";
RL J. Bacteriol. 194:195-196(2012).
CC -!- FUNCTION: Required for chromosome condensation and partitioning.
CC {ECO:0000255|HAMAP-Rule:MF_01894}.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01894}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01894}.
CC -!- DOMAIN: Contains large globular domains required for ATP hydrolysis at
CC each terminus and a third globular domain forming a flexible SMC hinge
CC near the middle of the molecule. These domains are separated by coiled-
CC coil structures. {ECO:0000255|HAMAP-Rule:MF_01894}.
CC -!- SIMILARITY: Belongs to the SMC family. {ECO:0000255|HAMAP-
CC Rule:MF_01894}.
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DR EMBL; AL935263; CCC78943.1; -; Genomic_DNA.
DR RefSeq; WP_011101482.1; NC_004567.2.
DR RefSeq; YP_004889457.1; NC_004567.2.
DR AlphaFoldDB; Q88WJ9; -.
DR SMR; Q88WJ9; -.
DR STRING; 220668.lp_1632; -.
DR PRIDE; Q88WJ9; -.
DR EnsemblBacteria; CCC78943; CCC78943; lp_1632.
DR KEGG; lpl:lp_1632; -.
DR PATRIC; fig|220668.9.peg.1379; -.
DR eggNOG; COG1196; Bacteria.
DR HOGENOM; CLU_001042_2_2_9; -.
DR OMA; HNKIAME; -.
DR PhylomeDB; Q88WJ9; -.
DR BioCyc; LPLA220668:G1GW0-1406-MON; -.
DR Proteomes; UP000000432; Chromosome.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR Gene3D; 3.40.50.300; -; 2.
DR HAMAP; MF_01894; Smc_prok; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR InterPro; IPR011890; SMC_prok.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF75553; SSF75553; 1.
DR TIGRFAMs; TIGR02168; SMC_prok_B; 1.
PE 3: Inferred from homology;
KW ATP-binding; Coiled coil; Cytoplasm; DNA-binding; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..1185
FT /note="Chromosome partition protein Smc"
FT /id="PRO_0000409275"
FT DOMAIN 519..637
FT /note="SMC hinge"
FT REGION 300..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 228..503
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
FT COILED 675..928
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
FT COILED 989..1025
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
FT BINDING 32..39
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
SQ SEQUENCE 1185 AA; 131883 MW; D291DAE0382FEF3E CRC64;
MQLKSLEISG FKSFADKTKI DFQAGMTGIV GPNGSGKSNI IEAIRWVLGE QAVKSLRGTK
MTDVIFAGSA NRKPLNMAKV TITFDNSDHF LPLDYAEVSI TRKLFRNGDS DYLINNQSCR
LKDITNLMID TGLGKDSFSV ISQGRVEAVF NAKPEERRSI IEDVAGVLKY KKDKFTTENK
LAETTDYLDR VNDIIAELNQ QKGPLEEQAS LARDYQDQKQ KFDYLDRSRL VKKLTIARDQ
LQGVNEKLAS AKALVAKYQQ QVDAGATKLA NLKTQQTAQL KQKDELVAQN LELIKTIENT
QGQQGVDAER RQNQQSEQER LTASLTATEQ QIATQTEQQT QLEQTLSEQQ AQVKAVKAQV
AELTTATSAA GRQQLADELE KLRNAYIDEK QVQAELNNEA KNLVKQHQQS GSQSTALAER
LAQAQANLKR VQTTVDVHNR EQRDLENQVS QQQATLTAQQ AQVKTNAERI DEQQQRWLDA
AGLMQREKSR LEALQAVQER YTNFYAGVRM VLQHRQQFSG VAGAVSELLT VPDQYTKAVE
VALGGQLQNI VCDTQQTAKT VVNFLKQNHA GRATFLPIER ITARQLPVNT ERDLSQQPGV
LGVASELVDC ESRLTAIKRY LLGTTAIVDT LDHAMAISRS RRFRCKLVTI DGETIAASGA
ITGGATRHDD NGLLQQQQSA EKIAANVAQM QSELVTYEQG LADLKKANQD LTVQVETTRQ
QLSELKDRLS QTQAQLQAAQ SEQTQLSRQV KALTYEQQQT QADDSYEDLV ARNQQAQAAN
AAKLKDYQDQ MKTVQQQQTD YESYQQTQTT KLQAQREQLI TLQEHVKQTQ RQLEQCQATL
AQNEETKKQI QADLTAIKTT LASQQMSVAE RDTVLKTAKA KQAAVEEQRK TCEQQLATLN
DQVEELSTQQ VRLQQLAAAA TDDYRRLELS QTKLTGEVDH ATADLAEKYQ LTVAAAQADV
SGLALPAITE QLKLLKRGLD EIGTVNLGAI DEFERVKERF DFLNNQASDL TEAKEHLLQT
MADLDTTVAT RFKTAFDQVA SEFSTIFEQM FGGGKAELIL TDPEHLLTSG VDIMAQPPGK
KFQRLSLLSG GERALTAITL LFAILAVRPV PFSILDEAEA ALDDANVDRF SQYLNDFQTG
TQFVIITHRK GTMMHADVLY GVTMEESGVS KMVSVSLADL KDEQK
