ID   SMC_METJA               Reviewed;        1169 AA.
AC   Q59037;
DT   29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 2.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Chromosome partition protein Smc {ECO:0000255|HAMAP-Rule:MF_01894};
GN   Name=smc {ECO:0000255|HAMAP-Rule:MF_01894}; OrderedLocusNames=MJ1643;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
RN   [2]
RP   SEQUENCE REVISION.
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RL   Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for chromosome condensation and partitioning.
CC       {ECO:0000255|HAMAP-Rule:MF_01894}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01894}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01894}.
CC   -!- DOMAIN: Contains large globular domains required for ATP hydrolysis at
CC       each terminus and a third globular domain forming a flexible SMC hinge
CC       near the middle of the molecule. These domains are separated by coiled-
CC       coil structures. {ECO:0000255|HAMAP-Rule:MF_01894}.
CC   -!- SIMILARITY: Belongs to the SMC family. {ECO:0000255|HAMAP-
CC       Rule:MF_01894}.
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DR   EMBL; L77117; AAB99663.1; -; Genomic_DNA.
DR   PIR; A64505; A64505.
DR   RefSeq; WP_010871167.1; NC_000909.1.
DR   AlphaFoldDB; Q59037; -.
DR   SMR; Q59037; -.
DR   STRING; 243232.MJ_1643; -.
DR   EnsemblBacteria; AAB99663; AAB99663; MJ_1643.
DR   GeneID; 1452552; -.
DR   KEGG; mja:MJ_1643; -.
DR   eggNOG; arCOG00371; Archaea.
DR   HOGENOM; CLU_001042_2_2_2; -.
DR   InParanoid; Q59037; -.
DR   OMA; HNKIAME; -.
DR   OrthoDB; 1023at2157; -.
DR   PhylomeDB; Q59037; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 2.
DR   HAMAP; MF_01894; Smc_prok; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   InterPro; IPR024704; SMC.
DR   InterPro; IPR010935; SMC_hinge.
DR   InterPro; IPR036277; SMC_hinge_sf.
DR   InterPro; IPR011890; SMC_prok.
DR   Pfam; PF06470; SMC_hinge; 1.
DR   Pfam; PF02463; SMC_N; 2.
DR   PIRSF; PIRSF005719; SMC; 1.
DR   SMART; SM00968; SMC_hinge; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF75553; SSF75553; 1.
DR   TIGRFAMs; TIGR02169; SMC_prok_A; 1.
DR   TIGRFAMs; TIGR02168; SMC_prok_B; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coiled coil; Cytoplasm; DNA-binding; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..1169
FT                   /note="Chromosome partition protein Smc"
FT                   /id="PRO_0000119031"
FT   DOMAIN          523..636
FT                   /note="SMC hinge"
FT   COILED          166..507
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
FT   COILED          676..1030
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
FT   BINDING         32..39
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01894"
SQ   SEQUENCE   1169 AA;  136635 MW;  B63CCE34E4C03F36 CRC64;
     MVTLEKIELK NFKSFKKLSL DIPKGFTAIV GPNGSGKSNI VDAILFVLGK TSAKKLRANR
     FSGLITYHNG KRADFAEVCL YFTNENNAFN VNADKVGILR RIKSSGETDY YLVWKENDKE
     KRKKMTKHEI IDLFRRLGLL GDNVISQGDL LKIINISPIE RRKIIDEISG IAEFDEKKKK
     AEEELKKARE LIEMIDIRIS EVENNLKKLK KEKEDAEKYI KLNEELKAAK YALILKKVSY
     LNVLLENIQN DIKNLEELKN EFLSKVREID VEIENLKLRL NNIINELNEK GNEEVLELHK
     SIKELEVEIE NDKKVLDSSI NELKKVEVEI ENKKKEIKET QKKIIENRDS IIEKEQQIKE
     IEEKIKNLNY EKERLKEAIA ESESIIKHLK ESEMEIADEI AKNQNELYRL KKELNDLDNL
     INRKNFEIEK NNEMIKKLKE ELETVEDVDT KPLYLELENL NVEIEFSKRG IKELEEKKKE
     LQAKLDELHA EYVKENARIK ALKEMEELSM DRAIREILNA NLPGIIDIVG NLGKTKIEYK
     TAIEVAAGNR LNHIVVKRMD DAVRAIKYLK ERKLGRATFL PLDRIEGREA YYIDEDGVIG
     RAIDLVEFDE KYRRVFEYVF GNTVVVENID IAKELAKKYR KVRFVTLDGD VIEPSGAMIG
     GTFKSKAKIK VDVDLSKLNK IADEIIAIES ELRKIKEEIE RLSKIVKRSS AKKMEIENTL
     EIIKKNEMRK REIAEKNTIK IKELELKNKD ILEELEELNL KREEILNRIN EIESKINELI
     ERREKIINEL KEYESDENLK RMNEIEGELK ILEKEKAKLK NEIDKGLTLV KEILIPKIEE
     LNKKVSELIN KKVILEKNIS FYKESIEKNL SILEEKRKRY EELAKNLKEL TEKKEQLEKE
     IETLERERRE ILRKVRDIEN RINELMVEKA KYESKLEEEE RKLYLCEKVD VSKELEKKDI
     EELEIYIGEL ENEIKSLEPV NMRAIEDYNY VAERYKELIE KRKEYERDEK KYLQLMEELE
     NKKKEVFMEV FNKVAKNFEE VYKEIGGIGK LSLENEKNPF EGGILIDASP RGKKLLSLDA
     MSGGEKSLTA LAFLFAIQRL NPSPFYVLDE VDAALDVKNV SLIADMIKNA SKDSQFIVIS
     HREQMVSKAD VVYGVYMENG LSKVVGIRL