ID   ABFC_ASPCL              Reviewed;         505 AA.
AC   A1CQC3;
DT   15-JUN-2010, integrated into UniProtKB/Swiss-Prot.
DT   15-JUN-2010, sequence version 2.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Probable alpha-L-arabinofuranosidase C;
DE            Short=ABF C;
DE            Short=Arabinosidase C;
DE            EC=3.2.1.55;
DE   Flags: Precursor;
GN   Name=abfC; ORFNames=ACLA_025610;
OS   Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS   NRRL 1 / QM 1276 / 107).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=344612;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1;
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- FUNCTION: Alpha-L-arabinofuranosidase involved in the degradation of
CC       arabinoxylan, a major component of plant hemicellulose. Acts only on
CC       small linear 1,5-alpha-linked L-arabinofuranosyl oligosaccharides (By
CC       similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside
CC         residues in alpha-L-arabinosides.; EC=3.2.1.55;
CC   -!- PATHWAY: Glycan metabolism; L-arabinan degradation.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 51 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAW07844.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; DS027059; EAW07844.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_001269270.1; XM_001269269.1.
DR   AlphaFoldDB; A1CQC3; -.
DR   SMR; A1CQC3; -.
DR   STRING; 5057.CADACLAP00002990; -.
DR   PRIDE; A1CQC3; -.
DR   GeneID; 4702002; -.
DR   KEGG; act:ACLA_025610; -.
DR   eggNOG; ENOG502QRW4; Eukaryota.
DR   OrthoDB; 321051at2759; -.
DR   UniPathway; UPA00667; -.
DR   Proteomes; UP000006701; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0046556; F:alpha-L-arabinofuranosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0031222; P:arabinan catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046373; P:L-arabinose metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.40.1180; -; 1.
DR   InterPro; IPR010720; Alpha-L-AF_C.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   Pfam; PF06964; Alpha-L-AF_C; 1.
DR   SMART; SM00813; Alpha-L-AF_C; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Glycoprotein; Glycosidase; Hydrolase;
KW   Polysaccharide degradation; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..?
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..505
FT                   /note="Probable alpha-L-arabinofuranosidase C"
FT                   /id="PRO_0000394610"
FT   CARBOHYD        152
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        269
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        438
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   505 AA;  56416 MW;  B31B9769132A51C1 CRC64;
     MTTFTKLSEQ ETPSIAVHAS RRISKINPNI YAGFTEHMGR CIYGGIYDPG NPLSDENGFR
     KDVLEALKEL NIPVVRYPGG NFMATYHWID GVGPKDQRPS RPELAWLGTE TNQFGTDEFM
     KWCELLGTEP YFCLNFGTGT LDEALAWVEY CNGTRDTYYA NLRRKNGREE PYNIKYWALG
     NEVWGPWQVA QTTKEEYAHK AYQWAKALKL LDPTLKLILC GQDGTASWDY YTLKHCILPV
     NSPLSTSAVP LIDMHSIHLY TSSSSHLPNV TAPLAAERAI EITSSLIDLA MIENGVPNTQ
     LRPTICFDEW NVWDPIRAEG SKGAEESYTL SDALAVAVWL NVFVRKSKDV GMACIAQTVN
     VISPLMTTKD GIIKQTTWWP LYLFSKYMRG WTINTHVSCG TYEGETAPSW VRTVKDTPWL
     DVSATLGEDG YVNVAVVNIS EDKDIESKFE GAAGEVAVFT VNGDSVSACN MNGKQEVGVT
     ESTWDGKGAY AFPKHSLTLL RWKAE