BIM3_ARATH
ID BIM3_ARATH Reviewed; 298 AA.
AC Q9FMB6; B4F7P8;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Transcription factor BIM3;
DE AltName: Full=BES1-interacting Myc-like protein 3;
DE AltName: Full=Basic helix-loop-helix protein 141;
DE Short=AtbHLH141;
DE Short=bHLH 141;
DE AltName: Full=Transcription factor EN 127;
DE AltName: Full=bHLH transcription factor bHLH141;
GN Name=BIM3; Synonyms=BHLH141, EN127; OrderedLocusNames=At5g38860;
GN ORFNames=K15E6.40, K15E6.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=15208423; DOI=10.1104/pp.104.042176;
RA Gong W., Shen Y.-P., Ma L.-G., Pan Y., Du Y.-L., Wang D.-H., Yang J.-Y.,
RA Hu L.-D., Liu X.-F., Dong C.-X., Ma L., Chen Y.-H., Yang X.-Y., Gao Y.,
RA Zhu D., Tan X., Mu J.-Y., Zhang D.-B., Liu Y.-L., Dinesh-Kumar S.P., Li Y.,
RA Wang X.-P., Gu H.-Y., Qu L.-J., Bai S.-N., Lu Y.-T., Li J.-Y., Zhao J.-D.,
RA Zuo J., Huang H., Deng X.-W., Zhu Y.-X.;
RT "Genome-wide ORFeome cloning and analysis of Arabidopsis transcription
RT factor genes.";
RL Plant Physiol. 135:773-782(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA De Los Reyes C., Quan R., Chen H., Bautista V.R., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=14600211; DOI=10.1105/tpc.151140;
RA Bailey P.C., Martin C., Toledo-Ortiz G., Quail P.H., Huq E., Heim M.A.,
RA Jakoby M., Werber M., Weisshaar B.;
RT "Update on the basic helix-loop-helix transcription factor gene family in
RT Arabidopsis thaliana.";
RL Plant Cell 15:2497-2502(2003).
RN [6]
RP IDENTIFICATION, AND INTERACTION WITH BZR2/BES1.
RX PubMed=15680330; DOI=10.1016/j.cell.2004.11.044;
RA Yin Y., Vafeados D., Tao Y., Yoshida S., Asami T., Chory J.;
RT "A new class of transcription factors mediates brassinosteroid-regulated
RT gene expression in Arabidopsis.";
RL Cell 120:249-259(2005).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12897250; DOI=10.1105/tpc.013839;
RA Toledo-Ortiz G., Huq E., Quail P.H.;
RT "The Arabidopsis basic/helix-loop-helix transcription factor family.";
RL Plant Cell 15:1749-1770(2003).
CC -!- FUNCTION: Positive brassinosteroid-signaling protein.
CC -!- SUBUNIT: Homodimer (Probable). Interacts with the N-terminus of
CC BZR2/BES1. {ECO:0000269|PubMed:15680330, ECO:0000305}.
CC -!- INTERACTION:
CC Q9FMB6; Q9LEZ3: BIM1; NbExp=6; IntAct=EBI-617113, EBI-617095;
CC Q9FMB6; Q9CAA4: BIM2; NbExp=6; IntAct=EBI-617113, EBI-4476396;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR EMBL; AB009048; BAB08642.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94367.1; -; Genomic_DNA.
DR EMBL; AJ630499; CAG25872.1; -; mRNA.
DR EMBL; AY568671; AAS79561.1; -; mRNA.
DR EMBL; BT033131; ACF28392.1; -; mRNA.
DR RefSeq; NP_198702.2; NM_123247.5.
DR AlphaFoldDB; Q9FMB6; -.
DR SMR; Q9FMB6; -.
DR BioGRID; 19128; 10.
DR IntAct; Q9FMB6; 9.
DR STRING; 3702.AT5G38860.1; -.
DR PaxDb; Q9FMB6; -.
DR PRIDE; Q9FMB6; -.
DR ProteomicsDB; 240374; -.
DR EnsemblPlants; AT5G38860.1; AT5G38860.1; AT5G38860.
DR GeneID; 833877; -.
DR Gramene; AT5G38860.1; AT5G38860.1; AT5G38860.
DR KEGG; ath:AT5G38860; -.
DR Araport; AT5G38860; -.
DR TAIR; locus:2152262; AT5G38860.
DR eggNOG; ENOG502QSVQ; Eukaryota.
DR HOGENOM; CLU_030221_0_0_1; -.
DR InParanoid; Q9FMB6; -.
DR OMA; RSFCNDI; -.
DR OrthoDB; 893619at2759; -.
DR PhylomeDB; Q9FMB6; -.
DR PRO; PR:Q9FMB6; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FMB6; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR GO; GO:0006351; P:transcription, DNA-templated; IMP:TAIR.
DR Gene3D; 4.10.280.10; -; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR044295; BIM1/2/3.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR PANTHER; PTHR46412; PTHR46412; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; SSF47459; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..298
FT /note="Transcription factor BIM3"
FT /id="PRO_0000127155"
FT DOMAIN 33..85
FT /note="bHLH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 263..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 298 AA; 33950 MW; 429B048CE75ADD91 CRC64;
MNSHDIDDQL EADVYSNLPS RNDSSTGRRN RNSCRSKHSE TEQRRRSKIN ERFQSLMDII
PQNQNDQKRD KASFLLEVIE YIHFLQEKVH MYEDSHQMWY QSPTKLIPWR NSHGSVAEEN
DHPQIVKSFS SNDKVAASSG FLLDTYNSVN PDIDSAVSTK IPEHSPVSAV SSYLRTEPSL
QFVQHDFWQP KTSCGTINCF TNELLTSDEK TSASLSTVCS QRVLNTLTEA LKSSGVNMSE
TMISVQLSLR KREDREYSVA AFASEDNGNS IADEEGDSPT ETRSFCNDID HSQKRIRR
