BIMA_EMENI
ID BIMA_EMENI Reviewed; 806 AA.
AC P17885; C8V2B7; Q5AZZ2;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 25-MAY-2022, entry version 132.
DE RecName: Full=Protein bimA;
GN Name=bimA; ORFNames=AN6138;
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=R153;
RX PubMed=1770001; DOI=10.1242/jcs.99.4.711;
RA O'Donnell K.L., Osmani A.H., Osmani S.A., Morris N.R.;
RT "bimA encodes a member of the tetratricopeptide repeat family of proteins
RT and is required for the completion of mitosis in Aspergillus nidulans.";
RL J. Cell Sci. 99:711-719(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- FUNCTION: Required for the completion of mitosis in Aspergillus
CC nidulans.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the APC3/CDC27 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CBF70105.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=EAA57924.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; X59269; CAA41959.1; -; mRNA.
DR EMBL; AACD01000105; EAA57924.1; ALT_SEQ; Genomic_DNA.
DR EMBL; BN001301; CBF70105.1; ALT_SEQ; Genomic_DNA.
DR PIR; A53256; A53256.
DR RefSeq; XP_663742.1; XM_658650.1.
DR AlphaFoldDB; P17885; -.
DR SMR; P17885; -.
DR STRING; 162425.CADANIAP00006872; -.
DR EnsemblFungi; EAA57924; EAA57924; AN6138.2.
DR GeneID; 2871215; -.
DR KEGG; ani:AN6138.2; -.
DR eggNOG; KOG1126; Eukaryota.
DR HOGENOM; CLU_008850_0_1_1; -.
DR InParanoid; P17885; -.
DR OrthoDB; 280620at2759; -.
DR Proteomes; UP000000560; Chromosome I.
DR Proteomes; UP000005890; Unassembled WGS sequence.
DR GO; GO:0005680; C:anaphase-promoting complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0031145; P:anaphase-promoting complex-dependent catabolic process; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IBA:GO_Central.
DR GO; GO:0007091; P:metaphase/anaphase transition of mitotic cell cycle; IBA:GO_Central.
DR GO; GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 4.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR Pfam; PF00515; TPR_1; 2.
DR SMART; SM00028; TPR; 8.
DR SUPFAM; SSF48452; SSF48452; 3.
DR PROSITE; PS50005; TPR; 8.
DR PROSITE; PS50293; TPR_REGION; 2.
PE 2: Evidence at transcript level;
KW Cell cycle; Cell division; Mitosis; Nucleus; Reference proteome; Repeat;
KW TPR repeat.
FT CHAIN 1..806
FT /note="Protein bimA"
FT /id="PRO_0000106265"
FT REPEAT 76..109
FT /note="TPR 1"
FT REPEAT 127..160
FT /note="TPR 2"
FT REPEAT 513..546
FT /note="TPR 3"
FT REPEAT 581..614
FT /note="TPR 4"
FT REPEAT 616..648
FT /note="TPR 5"
FT REPEAT 649..682
FT /note="TPR 6"
FT REPEAT 684..716
FT /note="TPR 7"
FT REPEAT 751..784
FT /note="TPR 8"
FT REGION 202..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 260..399
FT /note="BimA domain"
FT REGION 353..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 401..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..255
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..348
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..444
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..460
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 806 AA; 89715 MW; F137BDE3A74C0457 CRC64;
MTPSTSHISS QLRQLIYYHL DNNLARNALF LAGRLHAYEP RTSEASYLLA LCYLQNGQVK
AAWETSKHFG SRGAHLGCSY VYAQACLDLG KYTDGINALE RSKGQWTSRN HWNKHSETRR
QHLPDAAAVL CLQGKLWQAH KEHNKAVECY AAALKLNPFM WDAFLNLCET GVDLRVSNIY
KMSPELYSMV SSAALEDVES QVLPPDGPLQ TQVNPNPSLD PFTAGTTRSD STSTHGSSAL
WEKLNGSTVS VASSGTGPHL PREGMETPGG QSSESDDPRV TNGNGTDVFE PPLAPAKKNR
TIQTIGGDHP MDPPPKMRPT GIRPRTRTKF ESDEGHTERD AGMGHRLGDR KRTVSGQVAH
PSVPHSTDQG VGQRRSVRLF NQIKPSTNKI SSTALGVKEG REVKKVRTTG NKARTTTSSN
VGRVVSGNNR RHAGEIHDGD SKEYRGTSST SNGSQNASSK LAISERTKSV EALAWILDLF
FKIASGYFCL SRYKCSDAIQ IFSSLSQGQR ETPWVLAQIG RAYYEQAMYT EAEKYFVRVK
AMAPSRLEDM EIYSTVLWHL KNDVELAYLA HELMDVDRLS PEAWCAVGNS FSHQRDHDQA
LKCFKRATQL DPHFAYGFTL QGHEYVANEE YDKALDAYRS GINADSRHYN AWYGLGTVYD
KMGKLDFAEQ HFRNAAKINP SNAVLICCIG LVLEKMNNPK SALIQYNRAC TLAPHSVLAR
FRKARALMKL QDLKSALTEL KVLKDMAPDE ANVHYLLGKL YKMLRDKGNA IKHFTTALNL
DPKAAQYIKD AMEALDDDEE DEEDMA
