SMH2_MAIZE
ID SMH2_MAIZE Reviewed; 298 AA.
AC B4FT40; Q6VSV3;
DT 14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Single myb histone 2;
DE AltName: Full=Protein SINGLE MYB HISTONE2;
GN Name=SMH2;
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=18937034; DOI=10.1007/s11103-008-9415-4;
RA Alexandrov N.N., Brover V.V., Freidin S., Troukhan M.E., Tatarinova T.V.,
RA Zhang H., Swaller T.J., Lu Y.-P., Bouck J., Flavell R.B., Feldmann K.A.;
RT "Insights into corn genes derived from large-scale cDNA sequencing.";
RL Plant Mol. Biol. 69:179-194(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. B73;
RX PubMed=19936069; DOI=10.1371/journal.pgen.1000740;
RA Soderlund C., Descour A., Kudrna D., Bomhoff M., Boyd L., Currie J.,
RA Angelova A., Collura K., Wissotski M., Ashley E., Morrow D., Fernandes J.,
RA Walbot V., Yu Y.;
RT "Sequencing, mapping, and analysis of 27,455 maize full-length cDNAs.";
RL PLoS Genet. 5:E1000740-E1000740(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 50-104, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. B73;
RX PubMed=14576282; DOI=10.1104/pp.103.026856;
RA Marian C.O., Bordoli S.J., Goltz M., Santarella R.A., Jackson L.P.,
RA Danilevskaya O., Beckstette M., Meeley R., Bass H.W.;
RT "The maize Single myb histone 1 gene, Smh1, belongs to a novel gene family
RT and encodes a protein that binds telomere DNA repeats in vitro.";
RL Plant Physiol. 133:1336-1350(2003).
CC -!- FUNCTION: Binds preferentially double-stranded telomeric repeats, but
CC may also bind to the single telomeric strand. {ECO:0000250}.
CC -!- SUBUNIT: Forms a homodimer and heterodimers. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625,
CC ECO:0000255|PROSITE-ProRule:PRU00837}. Chromosome {ECO:0000255|PROSITE-
CC ProRule:PRU00837}. Nucleus, nucleolus {ECO:0000250}. Chromosome,
CC telomere {ECO:0000305}. Note=Localized to the nucleolus during
CC interphase. {ECO:0000250}.
CC -!- DOMAIN: HTH myb-type domain confers double-stranded telomeric DNA-
CC binding while the H15 domain is involved in non-specific DNA-protein
CC interaction and multimerization. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the histone H1/H5 family. SMH subfamily.
CC {ECO:0000255|PROSITE-ProRule:PRU00837}.
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DR EMBL; EU962228; ACG34346.1; -; mRNA.
DR EMBL; BT040278; ACF85283.1; -; mRNA.
DR EMBL; AY328855; AAR01212.1; -; Genomic_DNA.
DR RefSeq; NP_001141049.1; NM_001147577.1.
DR AlphaFoldDB; B4FT40; -.
DR SMR; B4FT40; -.
DR STRING; 4577.GRMZM2G087817_P02; -.
DR PaxDb; B4FT40; -.
DR PRIDE; B4FT40; -.
DR GeneID; 100273130; -.
DR KEGG; zma:100273130; -.
DR eggNOG; ENOG502QSU2; Eukaryota.
DR HOGENOM; CLU_047477_0_1_1; -.
DR OMA; RNHASAM; -.
DR OrthoDB; 1324883at2759; -.
DR Proteomes; UP000007305; Chromosome 3.
DR ExpressionAtlas; B4FT40; baseline and differential.
DR GO; GO:0000785; C:chromatin; ISS:UniProtKB.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.
DR GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0003691; F:double-stranded telomeric DNA binding; ISS:UniProtKB.
DR GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR GO; GO:0043047; F:single-stranded telomeric DNA binding; ISS:UniProtKB.
DR GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR005818; Histone_H1/H5_H15.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR044597; SMH1-6.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46267; PTHR46267; 1.
DR Pfam; PF00538; Linker_histone; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM00526; H15; 1.
DR SMART; SM00717; SANT; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS51504; H15; 1.
DR PROSITE; PS51294; HTH_MYB; 1.
PE 2: Evidence at transcript level;
KW Chromosome; Coiled coil; DNA-binding; Nucleus; Reference proteome;
KW Telomere; Transcription; Transcription regulation.
FT CHAIN 1..298
FT /note="Single myb histone 2"
FT /id="PRO_0000429014"
FT DOMAIN 1..61
FT /note="HTH myb-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 124..192
FT /note="H15"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT DNA_BIND 28..57
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT COILED 237..278
FT /evidence="ECO:0000255"
SQ SEQUENCE 298 AA; 32629 MW; A64E563C3F86C21D CRC64;
MGVPKQRWTP EEEAALKAGV AKHGPGKWRT ILRDSDFSAL LRLRSNVDLK DKWRNLSVTA
GGYGSREKAR MALKKGRRVV PKLTAEPMDV DEKDMDNAHD TVIDVEPLAM AFEPLPFLES
PDKSVARLDD LIVEAIRKLN EPSGSNKAVI SGYIEDQYWP PADFQYLLST KLKSLVNSGK
LIKVNQKYRI APSSSLGGIS TKVSSSEGMN TENNNVKRLT KPQVVAELEK MKGMTREEAA
AFAAKAVAEA EVAMAEAEEA ARVAEAAEND AEAAKAFLDA VILSMRNRNA ASMILRAC
