ID   SMI1_ASHGO              Reviewed;         657 AA.
AC   Q75AQ9;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2013, sequence version 2.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=KNR4/SMI1 homolog;
GN   OrderedLocusNames=ADL139W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION, AND SEQUENCE REVISION TO 592.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- SIMILARITY: Belongs to the KNR4/SMI1 family. {ECO:0000305}.
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DR   EMBL; AE016817; AAS51781.2; -; Genomic_DNA.
DR   RefSeq; NP_983957.2; NM_209310.2.
DR   AlphaFoldDB; Q75AQ9; -.
DR   SMR; Q75AQ9; -.
DR   STRING; 33169.AAS51781; -.
DR   EnsemblFungi; AAS51781; AAS51781; AGOS_ADL139W.
DR   GeneID; 4620099; -.
DR   KEGG; ago:AGOS_ADL139W; -.
DR   eggNOG; ENOG502QTAZ; Eukaryota.
DR   HOGENOM; CLU_027501_3_0_1; -.
DR   InParanoid; Q75AQ9; -.
DR   OMA; EESTIWR; -.
DR   Proteomes; UP000000591; Chromosome IV.
DR   GO; GO:0005935; C:cellular bud neck; IEA:EnsemblFungi.
DR   GO; GO:0000131; C:incipient cellular bud site; IEA:EnsemblFungi.
DR   GO; GO:0042546; P:cell wall biogenesis; IEA:InterPro.
DR   GO; GO:0032995; P:regulation of fungal-type cell wall biogenesis; IBA:GO_Central.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IEA:EnsemblFungi.
DR   Gene3D; 3.40.1580.10; -; 1.
DR   InterPro; IPR009203; Knr4/Smi1.
DR   InterPro; IPR018958; Knr4/Smi1-like_dom.
DR   InterPro; IPR037883; Knr4/Smi1-like_sf.
DR   Pfam; PF09346; SMI1_KNR4; 1.
DR   PIRSF; PIRSF017023; KNR4; 1.
DR   SMART; SM00860; SMI1_KNR4; 1.
DR   SUPFAM; SSF160631; SSF160631; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..657
FT                   /note="KNR4/SMI1 homolog"
FT                   /id="PRO_0000209872"
FT   REGION          168..193
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          366..402
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          416..657
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        168..188
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        416..446
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        474..490
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        501..522
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        533..599
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        623..651
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   657 AA;  71385 MW;  0B736081D1F6252B CRC64;
     MESLKRAWNQ LVYTFSTEDR YAEYTPQGST NVVGGEPFDT SNASRIQLNE FVDGAEVGGN
     DGVSECLLAW RHIDSWCSEH NPDLYATLSS PCTNNDIMWA EKDLAITFPA AVRASLRTHD
     GQEDVESMQG ASGLIYGLKL MGLEEVVIMT RTWRNVAANL QRQMARMEQQ QRAKSSSELP
     QTVTPQAVKQ KGYGKVDNQD YHANPHLQKD ISQNYNKQFK LDKLPKQGSI PPLAIQPVYA
     HPGWIPLVTD HAGNHIGVDL APGPKGKYAQ VILFGREFDT KFVVADNWGD FLLGFVNDLE
     KGNWLLVDNT DDYLNGEGDL VFVDHATRGP ILNYLAVLKK RSWEKWQSTK PTQPLTSASV
     ASFSTSSSVV NRPTPADAAG QARKTQGYSP MVPGASSNES VSFIPDSDVI MEESNLTQTD
     ASSKGTTKPA TPNPMTAPTV IRVSTPGSPS AAAEAPEPPK KATPPKAAKE TKTPTVTKES
     TPASDANVDT ELDSKNTETN EDTRATNTAH SMAPTVSSAI TDLTAIDEPV ATAGKPKDTE
     KTDDAKDVHE ANKQDLTKAN EAEAEENAVE PKDNEVSADS KVKARAESKS DHDSKTNNIP
     EKKVPQVTAK ALPESDRGQA SDAASTKSDK KAKPAEDPKE HDLKIEKLNE DFETVAL