SMIM3_MOUSE
ID SMIM3_MOUSE Reviewed; 60 AA.
AC Q99PE5; Q921E9;
DT 19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Small integral membrane protein 3;
DE AltName: Full=NGF-induced differentiation clone 67 protein;
DE AltName: Full=Small membrane protein NID67;
GN Name=Smim3; Synonyms=Nid67;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Brain;
RX PubMed=11288140; DOI=10.1002/jnr.1058;
RA Vician L., Silver A.L., Farias-Eisner R., Herschman H.R.;
RT "NID67, a small putative membrane protein, is preferentially induced by NGF
RT in PC12 pheochromocytoma cells.";
RL J. Neurosci. Res. 64:108-120(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AF313412; AAG53958.1; -; mRNA.
DR EMBL; BC012898; AAH12898.1; -; mRNA.
DR CCDS; CCDS37831.1; -.
DR RefSeq; NP_598894.1; NM_134133.2.
DR RefSeq; XP_006525544.1; XM_006525481.3.
DR RefSeq; XP_006525545.1; XM_006525482.3.
DR RefSeq; XP_011245099.1; XM_011246797.1.
DR AlphaFoldDB; Q99PE5; -.
DR SMR; Q99PE5; -.
DR STRING; 10090.ENSMUSP00000039285; -.
DR PaxDb; Q99PE5; -.
DR PRIDE; Q99PE5; -.
DR ProteomicsDB; 257205; -.
DR Antibodypedia; 71669; 4 antibodies from 4 providers.
DR Ensembl; ENSMUST00000042710; ENSMUSP00000039285; ENSMUSG00000038059.
DR GeneID; 106878; -.
DR KEGG; mmu:106878; -.
DR UCSC; uc008fag.1; mouse.
DR CTD; 85027; -.
DR MGI; MGI:1917088; Smim3.
DR VEuPathDB; HostDB:ENSMUSG00000038059; -.
DR eggNOG; ENOG502SGSH; Eukaryota.
DR GeneTree; ENSGT00390000009443; -.
DR HOGENOM; CLU_2941125_0_0_1; -.
DR InParanoid; Q99PE5; -.
DR OMA; YRIRTHP; -.
DR PhylomeDB; Q99PE5; -.
DR TreeFam; TF354124; -.
DR BioGRID-ORCS; 106878; 2 hits in 70 CRISPR screens.
DR ChiTaRS; Smim3; mouse.
DR PRO; PR:Q99PE5; -.
DR Proteomes; UP000000589; Chromosome 18.
DR RNAct; Q99PE5; protein.
DR Bgee; ENSMUSG00000038059; Expressed in blood and 170 other tissues.
DR ExpressionAtlas; Q99PE5; baseline and differential.
DR Genevisible; Q99PE5; MM.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0042802; F:identical protein binding; ISO:MGI.
DR InterPro; IPR035275; Smim3.
DR PANTHER; PTHR37859; PTHR37859; 1.
DR Pfam; PF17307; Smim3; 1.
PE 4: Predicted;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..60
FT /note="Small integral membrane protein 3"
FT /id="PRO_0000096817"
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000255"
FT SITE 19..20
FT /note="Cleavage"
FT /evidence="ECO:0000250|UniProtKB:Q99PE6"
FT CONFLICT 30
FT /note="T -> A (in Ref. 2; AAH12898)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 60 AA; 6526 MW; FCCFE113882A8EA0 CRC64;
MDAITQSPVD AVLPKHILDI WAIVLIILAT IVIMTSLFLC PATAVIIYRM RTHPVLNGAA
