ID   SMIM3_RAT               Reviewed;          60 AA.
AC   Q99PE6;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Small integral membrane protein 3;
DE   AltName: Full=NGF-induced differentiation clone 67 protein;
DE   AltName: Full=Small membrane protein NID67;
GN   Name=Smim3; Synonyms=Nid67;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=11288140; DOI=10.1002/jnr.1058;
RA   Vician L., Silver A.L., Farias-Eisner R., Herschman H.R.;
RT   "NID67, a small putative membrane protein, is preferentially induced by NGF
RT   in PC12 pheochromocytoma cells.";
RL   J. Neurosci. Res. 64:108-120(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Lung;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   CLEAVAGE AFTER ASP-19, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=26479776; DOI=10.1021/acs.jproteome.5b00820;
RA   Tsuchiya T., Osaki T., Minamino N., Sasaki K.;
RT   "Peptidomics for studying limited proteolysis.";
RL   J. Proteome Res. 14:4921-4931(2015).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AF313411; AAG53957.1; -; mRNA.
DR   EMBL; BC070515; AAH70515.1; -; mRNA.
DR   RefSeq; NP_775149.1; NM_173126.3.
DR   RefSeq; XP_006254831.1; XM_006254769.2.
DR   RefSeq; XP_017456352.1; XM_017600863.1.
DR   RefSeq; XP_017456353.1; XM_017600864.1.
DR   AlphaFoldDB; Q99PE6; -.
DR   SMR; Q99PE6; -.
DR   STRING; 10116.ENSRNOP00000026426; -.
DR   PaxDb; Q99PE6; -.
DR   Ensembl; ENSRNOT00000026426; ENSRNOP00000026426; ENSRNOG00000019536.
DR   GeneID; 286910; -.
DR   KEGG; rno:286910; -.
DR   UCSC; RGD:628864; rat.
DR   CTD; 85027; -.
DR   RGD; 628864; Smim3.
DR   eggNOG; ENOG502SGSH; Eukaryota.
DR   GeneTree; ENSGT00390000009443; -.
DR   HOGENOM; CLU_2941125_0_0_1; -.
DR   InParanoid; Q99PE6; -.
DR   OMA; YRIRTHP; -.
DR   PhylomeDB; Q99PE6; -.
DR   TreeFam; TF354124; -.
DR   PRO; PR:Q99PE6; -.
DR   Proteomes; UP000002494; Chromosome 18.
DR   Bgee; ENSRNOG00000019536; Expressed in heart and 19 other tissues.
DR   Genevisible; Q99PE6; RN.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; ISO:RGD.
DR   GO; GO:0007399; P:nervous system development; NAS:RGD.
DR   InterPro; IPR035275; Smim3.
DR   PANTHER; PTHR37859; PTHR37859; 1.
DR   Pfam; PF17307; Smim3; 1.
PE   1: Evidence at protein level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..60
FT                   /note="Small integral membrane protein 3"
FT                   /id="PRO_0000096818"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   SITE            19..20
FT                   /note="Cleavage"
FT                   /evidence="ECO:0000269|PubMed:26479776"
SQ   SEQUENCE   60 AA;  6568 MW;  851000DE2A647F4A CRC64;
     MDAISQSPVD VLLPKHILDI WAIVLIILAT VVIMTSLFLC PATAVIIYRM RTHPVLNGAV