ID   SMIM7_MOUSE             Reviewed;          75 AA.
AC   Q5RKS2;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Small integral membrane protein 7;
DE   Flags: Precursor;
GN   Name=Smim7;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Brain, and Mammary gland;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SMIM7 family. {ECO:0000305}.
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DR   EMBL; BC037511; AAH37511.1; -; mRNA.
DR   EMBL; BC055692; AAH55692.1; -; mRNA.
DR   CCDS; CCDS40390.1; -.
DR   RefSeq; NP_765984.1; NM_172396.3.
DR   AlphaFoldDB; Q5RKS2; -.
DR   BioGRID; 211739; 2.
DR   STRING; 10090.ENSMUSP00000127441; -.
DR   PhosphoSitePlus; Q5RKS2; -.
DR   MaxQB; Q5RKS2; -.
DR   PaxDb; Q5RKS2; -.
DR   PRIDE; Q5RKS2; -.
DR   ProteomicsDB; 257207; -.
DR   Antibodypedia; 27426; 17 antibodies from 8 providers.
DR   DNASU; 66818; -.
DR   Ensembl; ENSMUST00000167290; ENSMUSP00000127441; ENSMUSG00000044600.
DR   GeneID; 66818; -.
DR   KEGG; mmu:66818; -.
DR   UCSC; uc009mgh.1; mouse.
DR   CTD; 79086; -.
DR   MGI; MGI:1914068; Smim7.
DR   VEuPathDB; HostDB:ENSMUSG00000044600; -.
DR   eggNOG; ENOG502S4E0; Eukaryota.
DR   GeneTree; ENSGT00390000014626; -.
DR   HOGENOM; CLU_181165_0_0_1; -.
DR   InParanoid; Q5RKS2; -.
DR   OMA; IAMWNIF; -.
DR   OrthoDB; 1574851at2759; -.
DR   PhylomeDB; Q5RKS2; -.
DR   TreeFam; TF332999; -.
DR   BioGRID-ORCS; 66818; 3 hits in 72 CRISPR screens.
DR   ChiTaRS; Smim7; mouse.
DR   PRO; PR:Q5RKS2; -.
DR   Proteomes; UP000000589; Chromosome 8.
DR   RNAct; Q5RKS2; protein.
DR   Bgee; ENSMUSG00000044600; Expressed in aortic valve and 268 other tissues.
DR   ExpressionAtlas; Q5RKS2; baseline and differential.
DR   Genevisible; Q5RKS2; MM.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR037659; SMIM7.
DR   PANTHER; PTHR28622; PTHR28622; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..75
FT                   /note="Small integral membrane protein 7"
FT                   /id="PRO_0000342614"
FT   TOPO_DOM        18..53
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        75
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   75 AA;  8555 MW;  3B699A008B9A70C4 CRC64;
     MIGDILLFGT LLMNAGAVLN FKLKKKDTQG FGEESKEPST GDNIREFLLS LRYFRIFIAL
     WNVFMMLCMI VLFGS