ID   SMIM8_XENTR             Reviewed;          97 AA.
AC   Q28GF4;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Small integral membrane protein 8;
GN   Name=smim8; ORFNames=TEgg033e03.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=N6; TISSUE=Skeletal muscle;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SMIM8 family. {ECO:0000305}.
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DR   EMBL; CR761409; CAJ82213.1; -; mRNA.
DR   EMBL; BC121618; AAI21619.1; -; mRNA.
DR   RefSeq; NP_001016334.1; NM_001016334.3.
DR   RefSeq; XP_012818435.1; XM_012962981.2.
DR   RefSeq; XP_012818436.1; XM_012962982.2.
DR   RefSeq; XP_012818437.1; XM_012962983.1.
DR   RefSeq; XP_012818438.1; XM_012962984.2.
DR   RefSeq; XP_012818439.1; XM_012962985.2.
DR   RefSeq; XP_012818440.1; XM_012962986.2.
DR   RefSeq; XP_012818441.1; XM_012962987.2.
DR   RefSeq; XP_012818442.1; XM_012962988.2.
DR   RefSeq; XP_012818443.1; XM_012962989.2.
DR   RefSeq; XP_012818444.1; XM_012962990.2.
DR   RefSeq; XP_012818445.1; XM_012962991.2.
DR   RefSeq; XP_012818446.1; XM_012962992.2.
DR   RefSeq; XP_017949371.1; XM_018093882.1.
DR   AlphaFoldDB; Q28GF4; -.
DR   STRING; 8364.ENSXETP00000053789; -.
DR   PaxDb; Q28GF4; -.
DR   DNASU; 549088; -.
DR   Ensembl; ENSXETT00000053789; ENSXETP00000053789; ENSXETG00000025086.
DR   GeneID; 549088; -.
DR   KEGG; xtr:549088; -.
DR   CTD; 57150; -.
DR   Xenbase; XB-GENE-940262; smim8.
DR   eggNOG; ENOG502S4X3; Eukaryota.
DR   HOGENOM; CLU_170028_0_0_1; -.
DR   InParanoid; Q28GF4; -.
DR   OMA; IFMNIND; -.
DR   OrthoDB; 1574927at2759; -.
DR   PhylomeDB; Q28GF4; -.
DR   TreeFam; TF323863; -.
DR   Proteomes; UP000008143; Chromosome 5.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000025086; Expressed in 4-cell stage embryo and 12 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR026686; UPF0708.
DR   PANTHER; PTHR14274; PTHR14274; 1.
DR   Pfam; PF14937; DUF4500; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..97
FT                   /note="Small integral membrane protein 8"
FT                   /id="PRO_0000360400"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   97 AA;  10990 MW;  8EAD420EB1A8D89B CRC64;
     MSSPSSESSN AKSSPPKEEY RTPGLRGVKT TTLFRAVNPE LFIKPNKPVM VFGIVTITMC
     VAYIAYLHAT EENKRELYEA VDSEGNRYTR RKSSKWD