ID   BIN3_XENLA              Reviewed;         252 AA.
AC   Q5PPZ5;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Bridging integrator 3 homolog;
GN   Name=bin3;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in cytokinesis and septation where it has a role in
CC       the localization of F-actin. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
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DR   EMBL; BC087428; AAH87428.1; -; mRNA.
DR   RefSeq; NP_001088770.1; NM_001095301.1.
DR   AlphaFoldDB; Q5PPZ5; -.
DR   SMR; Q5PPZ5; -.
DR   DNASU; 496034; -.
DR   GeneID; 496034; -.
DR   KEGG; xla:496034; -.
DR   CTD; 496034; -.
DR   Xenbase; XB-GENE-999572; bin3.L.
DR   OrthoDB; 1172471at2759; -.
DR   Proteomes; UP000186698; Chromosome 3L.
DR   Bgee; 496034; Expressed in testis and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   CDD; cd07590; BAR_Bin3; 1.
DR   Gene3D; 1.20.1270.60; -; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR004148; BAR_dom.
DR   InterPro; IPR037428; Bin3_BAR.
DR   Pfam; PF03114; BAR; 1.
DR   SMART; SM00721; BAR; 1.
DR   SUPFAM; SSF103657; SSF103657; 1.
DR   PROSITE; PS51021; BAR; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Coiled coil; Cytoplasm; Cytoskeleton;
KW   Reference proteome; Septation.
FT   CHAIN           1..252
FT                   /note="Bridging integrator 3 homolog"
FT                   /id="PRO_0000192958"
FT   DOMAIN          8..231
FT                   /note="BAR"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00361"
FT   COILED          17..57
FT                   /evidence="ECO:0000255"
FT   COILED          119..150
FT                   /evidence="ECO:0000255"
FT   COILED          224..244
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   252 AA;  29383 MW;  6ADB71846DF740A3 CRC64;
     MSWNLFKGGP KKQIVPKTVE RDFEREYGKL QQLEDQIKKL QKDMKKSIEA DLAMSKSAVR
     ISSDLLGNPL CEPDVDFLQM VTALDTAMKR MDAFNQEKVN QIQKTVMDPL KRYSSVFPSL
     NMAVKRREQA LQDYKRLQTK VEKYEEKDKT GAMIAKLHQA REELRPVRDD FEAKNHQLLD
     EMPKFYNSRT DFFKPSFQSL IRAQVVYYTE MSRVFGDLAQ QVDEVQLSDA EREQENEARL
     AELRSLSIVA DD