SMIM9_MOUSE
ID SMIM9_MOUSE Reviewed; 137 AA.
AC Q3V0X1;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Small integral membrane protein 9;
DE Flags: Precursor;
GN Name=Smim9;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
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DR EMBL; AK132828; BAE21382.1; -; mRNA.
DR EMBL; AL808110; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS53113.1; -.
DR RefSeq; NP_001028958.1; NM_001033786.2.
DR AlphaFoldDB; Q3V0X1; -.
DR PaxDb; Q3V0X1; -.
DR PRIDE; Q3V0X1; -.
DR ProteomicsDB; 261439; -.
DR Antibodypedia; 71256; 4 antibodies from 4 providers.
DR Ensembl; ENSMUST00000101433; ENSMUSP00000098976; ENSMUSG00000073094.
DR Ensembl; ENSMUST00000165080; ENSMUSP00000132737; ENSMUSG00000073094.
DR GeneID; 434800; -.
DR KEGG; mmu:434800; -.
DR UCSC; uc009tps.1; mouse.
DR CTD; 100132963; -.
DR MGI; MGI:3588243; Smim9.
DR VEuPathDB; HostDB:ENSMUSG00000073094; -.
DR eggNOG; ENOG502TKME; Eukaryota.
DR GeneTree; ENSGT00390000005685; -.
DR HOGENOM; CLU_1864476_0_0_1; -.
DR InParanoid; Q3V0X1; -.
DR OMA; QRSWMSK; -.
DR OrthoDB; 1598115at2759; -.
DR PhylomeDB; Q3V0X1; -.
DR TreeFam; TF354094; -.
DR BioGRID-ORCS; 434800; 3 hits in 72 CRISPR screens.
DR ChiTaRS; Smim9; mouse.
DR PRO; PR:Q3V0X1; -.
DR Proteomes; UP000000589; Chromosome X.
DR RNAct; Q3V0X1; protein.
DR Bgee; ENSMUSG00000073094; Expressed in spermatid and 28 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR038853; Smim9.
DR PANTHER; PTHR41687; PTHR41687; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..137
FT /note="Small integral membrane protein 9"
FT /id="PRO_0000348248"
FT TOPO_DOM 24..84
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 85..105
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 106..137
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 137 AA; 15398 MW; 91E56BB16A85D2FC CRC64;
MKPLKLFCIG LLLCPLVCLL LETAPPPSAL LTLEVKEKTG LKSDAMGVFA IRKNTSDINR
QVSGLQRPWM TKFKNHLSDF FKSSIPPAAI FALFVTTAIM RAAIVNKRLE EPHRQWTIDQ
RSSLEMQNMN LIKLFGG
