ID   SMKR1_HUMAN             Reviewed;          65 AA.
AC   H3BMG3;
DT   06-MAR-2013, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2012, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=Small lysine-rich protein 1;
GN   Name=SMKR1;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K.,
RA   Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A.,
RA   Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H.,
RA   Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A.,
RA   Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P.,
RA   Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M.,
RA   Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S.,
RA   Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R.,
RA   Strowmatt C., Latreille P., Miller N., Johnson D., Murray J.,
RA   Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W.,
RA   Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A.,
RA   Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E.,
RA   Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A.,
RA   Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A.,
RA   Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R.,
RA   McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H.,
RA   Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; AC009244; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC050400; -; NOT_ANNOTATED_CDS; mRNA.
DR   CCDS; CCDS59077.1; -.
DR   RefSeq; NP_001182172.1; NM_001195243.1.
DR   AlphaFoldDB; H3BMG3; -.
DR   SMR; H3BMG3; -.
DR   BioGRID; 939143; 1.
DR   IntAct; H3BMG3; 1.
DR   STRING; 9606.ENSP00000454370; -.
DR   BioMuta; SMKR1; -.
DR   PaxDb; H3BMG3; -.
DR   PeptideAtlas; H3BMG3; -.
DR   PRIDE; H3BMG3; -.
DR   Antibodypedia; 77560; 4 antibodies from 4 providers.
DR   DNASU; 100287482; -.
DR   Ensembl; ENST00000462322.3; ENSP00000454370.1; ENSG00000240204.3.
DR   GeneID; 100287482; -.
DR   KEGG; hsa:100287482; -.
DR   MANE-Select; ENST00000462322.3; ENSP00000454370.1; NM_001195243.2; NP_001182172.1.
DR   UCSC; uc003voy.3; human.
DR   CTD; 100287482; -.
DR   GeneCards; SMKR1; -.
DR   HGNC; HGNC:43561; SMKR1.
DR   HPA; ENSG00000240204; Tissue enriched (testis).
DR   neXtProt; NX_H3BMG3; -.
DR   OpenTargets; ENSG00000240204; -.
DR   VEuPathDB; HostDB:ENSG00000240204; -.
DR   eggNOG; ENOG502SC1M; Eukaryota.
DR   GeneTree; ENSGT00640000091917; -.
DR   HOGENOM; CLU_173519_0_0_1; -.
DR   InParanoid; H3BMG3; -.
DR   OMA; FGWPNSK; -.
DR   OrthoDB; 1600290at2759; -.
DR   TreeFam; TF339494; -.
DR   PathwayCommons; H3BMG3; -.
DR   SignaLink; H3BMG3; -.
DR   BioGRID-ORCS; 100287482; 10 hits in 1057 CRISPR screens.
DR   Pharos; H3BMG3; Tdark.
DR   PRO; PR:H3BMG3; -.
DR   Proteomes; UP000005640; Chromosome 7.
DR   RNAct; H3BMG3; protein.
DR   Bgee; ENSG00000240204; Expressed in sperm and 124 other tissues.
DR   Genevisible; H3BMG3; HS.
DR   InterPro; IPR037760; SMKR1.
DR   PANTHER; PTHR37932; PTHR37932; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..65
FT                   /note="Small lysine-rich protein 1"
FT                   /id="PRO_0000421259"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   65 AA;  7091 MW;  414CABE86C30C0A1 CRC64;
     MPAKGKKGKG QGKSHGKKQK KPEVDILSPA AMLNLYYIAH NVADCLHLRG FHWPGAPKGK
     KGRSK