ID   SMOX1_SCHMA             Reviewed;         280 AA.
AC   Q26600;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Homeobox protein SMOX-1;
DE   Flags: Fragment;
GN   Name=SMOX-1;
OS   Schistosoma mansoni (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6183;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Puerto Rican;
RX   PubMed=1356008; DOI=10.1016/0925-4773(92)90035-i;
RA   Webster P.J., Mansour T.E.;
RT   "Conserved classes of homeodomains in Schistosoma mansoni, an early
RT   bilateral metazoan.";
RL   Mech. Dev. 38:25-32(1992).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
CC   -!- SIMILARITY: Belongs to the Antp homeobox family. {ECO:0000305}.
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DR   EMBL; M85306; AAA29928.1; -; mRNA.
DR   PIR; S27840; S27840.
DR   AlphaFoldDB; Q26600; -.
DR   SMR; Q26600; -.
DR   STRING; 6183.Smp_002640.1; -.
DR   eggNOG; KOG0489; Eukaryota.
DR   HOGENOM; CLU_338126_0_0_1; -.
DR   Proteomes; UP000008854; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017995; Homeobox_antennapedia.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR020479; Homeobox_metazoa.
DR   Pfam; PF00046; Homeodomain; 1.
DR   PRINTS; PR00025; ANTENNAPEDIA.
DR   PRINTS; PR00024; HOMEOBOX.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Homeobox; Nucleus; Reference proteome.
FT   CHAIN           <1..>280
FT                   /note="Homeobox protein SMOX-1"
FT                   /id="PRO_0000049310"
FT   DNA_BIND        229..>280
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          61..88
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           214..219
FT                   /note="Antp-type hexapeptide"
FT   NON_TER         1
FT   NON_TER         280
SQ   SEQUENCE   280 AA;  32194 MW;  B07606F990790544 CRC64;
     NSNNINLSYD DQQRLIYSGT EQKYPTSNQL KSYPNGLLNP FNGTNFMHPT IQSNSLITRH
     PNNNSFQLNT TNDSNNNNTT NNGNDSRSHL YDISTFNAQN PYSLTNTLNF NSRTMNNQLT
     MNDSMKLNGN LTLHDTNYHA LLNGSTSFGS TVFRSLVNSE NQSYLNSSTN MLMNSSLDNI
     NNSNDHSTLN DNNNDCIGQS LRQSGNSSES NVVVYPWMNP KGTDISVDQK RTRQTYTRYQ
     TLELEKEFHF NKYLTRRRRI EIAHTLTLTE RQIKIWFQNR