ID   SMOX5_SCHMA             Reviewed;         284 AA.
AC   Q26604;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Homeobox protein SMOX-5;
GN   Name=SMOX-5;
OS   Schistosoma mansoni (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6183;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Puerto Rican;
RX   PubMed=1356008; DOI=10.1016/0925-4773(92)90035-i;
RA   Webster P.J., Mansour T.E.;
RT   "Conserved classes of homeodomains in Schistosoma mansoni, an early
RT   bilateral metazoan.";
RL   Mech. Dev. 38:25-32(1992).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M85304; AAA29932.1; -; mRNA.
DR   PIR; S27843; S27843.
DR   AlphaFoldDB; Q26604; -.
DR   SMR; Q26604; -.
DR   STRING; 6183.Smp_158000.1; -.
DR   eggNOG; KOG0488; Eukaryota.
DR   HOGENOM; CLU_2200184_0_0_1; -.
DR   Proteomes; UP000008854; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   Pfam; PF00046; Homeodomain; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Homeobox; Nucleus; Reference proteome.
FT   CHAIN           1..284
FT                   /note="Homeobox protein SMOX-5"
FT                   /id="PRO_0000049313"
FT   DNA_BIND        37..96
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          117..172
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        127..155
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   284 AA;  33446 MW;  B367260C388BE6B6 CRC64;
     MTTSTMQQLK HDGDFSDELN ETSTIQFYNK VSQQRKRRKT RTTFSNCQLN ELENNFNRQR
     YLTPTDRDRI AKHLGLTNTQ VITWFQNRRA KLKREAEELE RDVMALRKQK QQKFTCLSLS
     DHDHEETQID DENEQGDNNN DDDGDDNDVE EDDGEEQEKN HTKYLTQPPS ISNILPSSLK
     HFPSSTLNTL EIDNKHETLN MNLFINPFSN EKCLKRNKDL IRQQCYLFNH HINNYCTVNN
     DNNINNNNNN NNRKNSIDGM NKGRSIKKGN KIWCPALELE QEIH