ID   SMP_ECOLI               Reviewed;         214 AA.
AC   P0AGC7; P18838; Q2M5T0;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Probable inner membrane protein Smp;
DE   Flags: Precursor;
GN   Name=ytjB; Synonyms=smp {ECO:0000303|PubMed:2684780};
GN   OrderedLocusNames=b4387, JW4350;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], SUBCELLULAR LOCATION, INDUCTION,
RP   POST-TRANSLATIONAL MODIFICATION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=K12;
RX   PubMed=2684780; DOI=10.1016/0378-1119(89)90047-4;
RA   Neuwald A.F., Stauffer G.V.;
RT   "An Escherichia coli membrane protein with a unique signal sequence.";
RL   Gene 82:219-228(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=7610040; DOI=10.1093/nar/23.12.2105;
RA   Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.;
RT   "Analysis of the Escherichia coli genome VI: DNA sequence of the region
RT   from 92.8 through 100 minutes.";
RL   Nucleic Acids Res. 23:2105-2119(1995).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 198-214.
RC   STRAIN=K12;
RX   PubMed=8206909; DOI=10.1016/s0021-9258(17)33977-7;
RA   Morris T.W., Reed K.E., Cronan J.E. Jr.;
RT   "Identification of the gene encoding lipoate-protein ligase A of
RT   Escherichia coli. Molecular cloning and characterization of the lplA gene
RT   and gene product.";
RL   J. Biol. Chem. 269:16091-16100(1994).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305|PubMed:2684780};
CC       Single-pass membrane protein {ECO:0000255}.
CC   -!- INDUCTION: The nucleotide sequence of the putative signal may have a
CC       regulatory function; it may form a perfect stem-loop (PubMed:2684780).
CC       {ECO:0000269|PubMed:2684780}.
CC   -!- PTM: The signal sequence may not be cleaved.
CC       {ECO:0000305|PubMed:2684780}.
CC   -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC       {ECO:0000269|PubMed:2684780}.
CC   -!- SIMILARITY: Belongs to the Smp family. {ECO:0000305}.
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DR   EMBL; M30784; AAA24635.1; -; Genomic_DNA.
DR   EMBL; X03046; CAA26853.1; -; Genomic_DNA.
DR   EMBL; U14003; AAA97283.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC77340.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE78376.1; -; Genomic_DNA.
DR   EMBL; L27665; AAA21739.1; -; Genomic_DNA.
DR   PIR; A26227; A26227.
DR   RefSeq; NP_418804.1; NC_000913.3.
DR   RefSeq; WP_000124615.1; NZ_STEB01000033.1.
DR   AlphaFoldDB; P0AGC7; -.
DR   SMR; P0AGC7; -.
DR   BioGRID; 4262788; 13.
DR   DIP; DIP-35920N; -.
DR   IntAct; P0AGC7; 6.
DR   STRING; 511145.b4387; -.
DR   jPOST; P0AGC7; -.
DR   PaxDb; P0AGC7; -.
DR   PRIDE; P0AGC7; -.
DR   EnsemblBacteria; AAC77340; AAC77340; b4387.
DR   EnsemblBacteria; BAE78376; BAE78376; BAE78376.
DR   GeneID; 66671725; -.
DR   GeneID; 946089; -.
DR   KEGG; ecj:JW4350; -.
DR   KEGG; eco:b4387; -.
DR   PATRIC; fig|1411691.4.peg.2298; -.
DR   EchoBASE; EB0944; -.
DR   eggNOG; COG3726; Bacteria.
DR   HOGENOM; CLU_093836_0_0_6; -.
DR   OMA; RQVDNTT; -.
DR   PhylomeDB; P0AGC7; -.
DR   BioCyc; EcoCyc:EG10951-MON; -.
DR   PRO; PR:P0AGC7; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019305; Uncharacterised_Smp.
DR   Pfam; PF10144; SMP_2; 1.
PE   2: Evidence at transcript level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome; Signal;
KW   Transmembrane; Transmembrane helix.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000255"
FT   CHAIN           31..214
FT                   /note="Probable inner membrane protein Smp"
FT                   /id="PRO_0000032802"
FT   TRANSMEM        164..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   214 AA;  24083 MW;  B8D261F2D1BF304E CRC64;
     MARTKLKFRL HRAVIVLFCL ALLVALMQGA SWFSQNHQRQ RNPQLEELAR TLARQVTLNV
     APLMRTDSPD EKRIQAILDQ LTDESRILDA GVYDEQGDLI ARSGESVEVR DRLALDGKKA
     GGYFNQQIVE PIAGKNGPLG YLRLTLDTHT LATEAQQVDN TTNILRLMLL LSLAIGVVLT
     RTLLQGKRTR WQQSPFLLTA SKPVPEEEES EKKE