ID   SMR13_ARATH             Reviewed;         108 AA.
AC   F4IWB3; Q9LIH4;
DT   30-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Cyclin-dependent protein kinase inhibitor SMR13 {ECO:0000303|PubMed:26546445};
DE   AltName: Full=Protein SIAMESE-RELATED 13 {ECO:0000303|PubMed:26546445};
GN   Name=SMR13 {ECO:0000303|PubMed:26546445};
GN   OrderedLocusNames=At3g20898 {ECO:0000312|Araport:AT3G20898};
GN   ORFNames=MFD22.1 {ECO:0000312|EMBL:BAB01899.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA   Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT   features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT   clones.";
RL   DNA Res. 7:217-221(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   FUNCTION, GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=26546445; DOI=10.1105/tpc.15.00489;
RA   Kumar N., Harashima H., Kalve S., Bramsiepe J., Wang K., Sizani B.L.,
RA   Bertrand L.L., Johnson M.C., Faulk C., Dale R., Simmons L.A.,
RA   Churchman M.L., Sugimoto K., Kato N., Dasanayake M., Beemster G.,
RA   Schnittger A., Larkin J.C.;
RT   "Functional conservation in the SIAMESE-RELATED family of cyclin-dependent
RT   kinase inhibitors in land plants.";
RL   Plant Cell 27:3065-3080(2015).
CC   -!- FUNCTION: Probable cyclin-dependent protein kinase (CDK) inhibitor that
CC       functions as a repressor of mitosis in the endoreduplication cell
CC       cycle. {ECO:0000269|PubMed:26546445}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB01899.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP001304; BAB01899.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002686; AEE76437.1; -; Genomic_DNA.
DR   RefSeq; NP_001154630.1; NM_001161158.2.
DR   AlphaFoldDB; F4IWB3; -.
DR   STRING; 3702.AT3G20898.1; -.
DR   PaxDb; F4IWB3; -.
DR   PRIDE; F4IWB3; -.
DR   EnsemblPlants; AT3G20898.1; AT3G20898.1; AT3G20898.
DR   GeneID; 7922426; -.
DR   Gramene; AT3G20898.1; AT3G20898.1; AT3G20898.
DR   KEGG; ath:AT3G20898; -.
DR   Araport; AT3G20898; -.
DR   TAIR; locus:5019474757; AT3G20898.
DR   eggNOG; ENOG502S7SX; Eukaryota.
DR   HOGENOM; CLU_128426_1_0_1; -.
DR   InParanoid; F4IWB3; -.
DR   OMA; QVPQHNN; -.
DR   OrthoDB; 1551731at2759; -.
DR   PRO; PR:F4IWB3; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; F4IWB3; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0045839; P:negative regulation of mitotic nuclear division; IBA:GO_Central.
DR   GO; GO:0032875; P:regulation of DNA endoreduplication; IEA:InterPro.
DR   InterPro; IPR040389; SMR.
DR   PANTHER; PTHR33142; PTHR33142; 1.
PE   4: Predicted;
KW   Cell cycle; Protein kinase inhibitor; Reference proteome.
FT   CHAIN           1..108
FT                   /note="Cyclin-dependent protein kinase inhibitor SMR13"
FT                   /id="PRO_0000438472"
SQ   SEQUENCE   108 AA;  12129 MW;  8F3E8D0B756DD8F5 CRC64;
     MASKKARKPN RAEKKLTRSC FKKQVPQHNN INTNTIYSVP SPSPAAVLTS PGGCCTPKAK
     KSRIPEMLTC PPAPKKQRVS KNCVLRRRQI VFFAPPEIEL FFVNAHDR