SMR16_ARATH
ID SMR16_ARATH Reviewed; 125 AA.
AC Q9LN05;
DT 30-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Cyclin-dependent protein kinase inhibitor SMR16 {ECO:0000303|PubMed:26546445};
DE AltName: Full=Protein SIAMESE-RELATED 16 {ECO:0000303|PubMed:26546445};
GN Name=SMR16 {ECO:0000303|PubMed:26546445};
GN OrderedLocusNames=At1g08035 {ECO:0000312|Araport:AT1G08035};
GN ORFNames=T6D22.11 {ECO:0000312|EMBL:AAF79825.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=26546445; DOI=10.1105/tpc.15.00489;
RA Kumar N., Harashima H., Kalve S., Bramsiepe J., Wang K., Sizani B.L.,
RA Bertrand L.L., Johnson M.C., Faulk C., Dale R., Simmons L.A.,
RA Churchman M.L., Sugimoto K., Kato N., Dasanayake M., Beemster G.,
RA Schnittger A., Larkin J.C.;
RT "Functional conservation in the SIAMESE-RELATED family of cyclin-dependent
RT kinase inhibitors in land plants.";
RL Plant Cell 27:3065-3080(2015).
CC -!- FUNCTION: Probable cyclin-dependent protein kinase (CDK) inhibitor that
CC functions as a repressor of mitosis in the endoreduplication cell
CC cycle. {ECO:0000250|UniProtKB:Q9LZ78}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC026875; AAF79825.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE28232.1; -; Genomic_DNA.
DR RefSeq; NP_683287.2; NM_148446.3.
DR AlphaFoldDB; Q9LN05; -.
DR STRING; 3702.AT1G08035.1; -.
DR PaxDb; Q9LN05; -.
DR PRIDE; Q9LN05; -.
DR EnsemblPlants; AT1G08035.1; AT1G08035.1; AT1G08035.
DR GeneID; 837319; -.
DR Gramene; AT1G08035.1; AT1G08035.1; AT1G08035.
DR KEGG; ath:AT1G08035; -.
DR Araport; AT1G08035; -.
DR TAIR; locus:504956111; AT1G08035.
DR HOGENOM; CLU_163607_0_0_1; -.
DR InParanoid; Q9LN05; -.
DR OMA; NEDRCEV; -.
DR OrthoDB; 1592392at2759; -.
DR PhylomeDB; Q9LN05; -.
DR PRO; PR:Q9LN05; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LN05; baseline and differential.
DR GO; GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR InterPro; IPR038971; SMR11/SMR16.
DR PANTHER; PTHR36310; PTHR36310; 1.
PE 3: Inferred from homology;
KW Cell cycle; Protein kinase inhibitor; Reference proteome.
FT CHAIN 1..125
FT /note="Cyclin-dependent protein kinase inhibitor SMR16"
FT /id="PRO_0000438475"
SQ SEQUENCE 125 AA; 13865 MW; EE7040BD198C3935 CRC64;
MVLLSFSRYC DTITMDYEEN SIEGTSGYVE PITPMISKGD SGIIAISPLC DHYNNHMRID
SLTTCSDEEI IESLYQNIFS IVLCLQTEES GYGSHTPVSA ACPGAPMKLT KLSRNIDPGF
QRKLF
