ID   BINL_STAAU              Reviewed;         197 AA.
AC   P18358;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Transposon Tn552 resolvase;
GN   Name=tnpR; Synonyms=binL;
OS   Staphylococcus aureus.
OG   Plasmid pI9789.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=NCTC 9789 / PS80;
RX   PubMed=2170815; DOI=10.1111/j.1365-2958.1990.tb00669.x;
RA   Rowland S.J., Dyke K.G.H.;
RT   "Tn552, a novel transposable element from Staphylococcus aureus.";
RL   Mol. Microbiol. 4:961-975(1990).
RN   [2]
RP   FUNCTION.
RC   STRAIN=NCTC 9789 / PS80;
RX   PubMed=2555186; DOI=10.1002/j.1460-2075.1989.tb08418.x;
RA   Rowland S.J., Dyke K.G.H.;
RT   "Characterization of the staphylococcal beta-lactamase transposon Tn552.";
RL   EMBO J. 8:2761-2773(1989).
CC   -!- FUNCTION: Resolvase catalyzes the resolution (a site-specific
CC       recombination) of the cointegrated replicon to yield the final
CC       transposition products. {ECO:0000269|PubMed:2555186}.
CC   -!- SIMILARITY: Belongs to the site-specific recombinase resolvase family.
CC       {ECO:0000305}.
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DR   EMBL; X52734; CAA36950.1; -; Genomic_DNA.
DR   AlphaFoldDB; P18358; -.
DR   SMR; P18358; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000150; F:DNA strand exchange activity; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1390; -; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR006118; Recombinase_CS.
DR   InterPro; IPR006119; Resolv_N.
DR   InterPro; IPR036162; Resolvase-like_N_sf.
DR   InterPro; IPR006120; Resolvase_HTH_dom.
DR   Pfam; PF02796; HTH_7; 1.
DR   Pfam; PF00239; Resolvase; 1.
DR   SMART; SM00857; Resolvase; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF53041; SSF53041; 1.
DR   PROSITE; PS00397; RECOMBINASES_1; 1.
DR   PROSITE; PS00398; RECOMBINASES_2; 1.
DR   PROSITE; PS51736; RECOMBINASES_3; 1.
PE   3: Inferred from homology;
KW   DNA integration; DNA recombination; DNA-binding; Plasmid;
KW   Transposable element.
FT   CHAIN           1..197
FT                   /note="Transposon Tn552 resolvase"
FT                   /id="PRO_0000196380"
FT   DOMAIN          1..136
FT                   /note="Resolvase/invertase-type recombinase catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
FT   DNA_BIND        163..182
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        9
FT                   /note="O-(5'-phospho-DNA)-serine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
SQ   SEQUENCE   197 AA;  22454 MW;  3FD1481D6F3A7417 CRC64;
     MKIGYARVST GLQNLNLQED RLNAYGSEKI FSDHISGSKS KRPGLDKAIE FARSGDTIVV
     WRLDRLGRNM EDLITLVNEL NERGVSFHSL EENITMDKST STGQLLFHLF AAFAEFERNL
     ILERSSAGRI AARARGRYGG RPEKLNQKDL NLLKTLYDNG TPIKTIAEQW QVSRTTIYRY
     LNKLEEKEDE KQGEVSN