ID   BINR_STAAU              Reviewed;         192 AA.
AC   P19241;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Transposon Tn552 DNA-invertase BinR;
GN   Name=resR; Synonyms=binR;
OS   Staphylococcus aureus.
OG   Plasmid pI9789.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Rowland S.J., Dyke K.G.H.;
RT   "A DNA invertase from Staphylococcus aureus is a member of the hin family
RT   of site-specific recombinases.";
RL   FEMS Microbiol. Lett. 50:253-258(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=NCTC 9789 / PS80;
RX   PubMed=2555186; DOI=10.1002/j.1460-2075.1989.tb08418.x;
RA   Rowland S.J., Dyke K.G.H.;
RT   "Characterization of the staphylococcal beta-lactamase transposon Tn552.";
RL   EMBO J. 8:2761-2773(1989).
CC   -!- FUNCTION: DNA-invertase, mediating the inversion of inv.
CC   -!- SIMILARITY: Belongs to the site-specific recombinase resolvase family.
CC       {ECO:0000305}.
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DR   EMBL; M36694; AAA26640.1; -; Genomic_DNA.
DR   EMBL; X16298; CAA34365.1; -; Genomic_DNA.
DR   PIR; S16509; S16509.
DR   RefSeq; WP_000690630.1; NZ_UHCQ01000001.1.
DR   RefSeq; YP_006937605.1; NC_013319.1.
DR   RefSeq; YP_006938736.1; NC_013351.1.
DR   RefSeq; YP_006938773.1; NC_013352.1.
DR   AlphaFoldDB; P19241; -.
DR   SMR; P19241; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000150; F:DNA strand exchange activity; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1390; -; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR006118; Recombinase_CS.
DR   InterPro; IPR006119; Resolv_N.
DR   InterPro; IPR036162; Resolvase-like_N_sf.
DR   InterPro; IPR006120; Resolvase_HTH_dom.
DR   Pfam; PF02796; HTH_7; 1.
DR   Pfam; PF00239; Resolvase; 1.
DR   SMART; SM00857; Resolvase; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF53041; SSF53041; 1.
DR   PROSITE; PS00397; RECOMBINASES_1; 1.
DR   PROSITE; PS00398; RECOMBINASES_2; 1.
DR   PROSITE; PS51736; RECOMBINASES_3; 1.
PE   3: Inferred from homology;
KW   DNA integration; DNA invertase; DNA recombination; DNA-binding; Plasmid;
KW   Transposable element.
FT   CHAIN           1..192
FT                   /note="Transposon Tn552 DNA-invertase BinR"
FT                   /id="PRO_0000196381"
FT   DOMAIN          1..136
FT                   /note="Resolvase/invertase-type recombinase catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
FT   DNA_BIND        163..182
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        9
FT                   /note="O-(5'-phospho-DNA)-serine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
SQ   SEQUENCE   192 AA;  21908 MW;  FE10802827029894 CRC64;
     MKIGYARVST GLQNLNLQED RLNQYGCEKI FSDHISGAKS KRPGLDRAIE FARSGDTIVV
     WRLDRLGRNM ADLITLVNEL NNRGVSFHSL EENITMDKSS STGQLLFHLF AAFAEFERNL
     ILERSSAGRI AARARGRYGG RPEKLNKQDL TLLKTLYDNG TPIKTIAEQW KVSRTTIYRY
     LNKLNNQENK DK