ID   SMTB_CHLAA              Reviewed;         405 AA.
AC   A9WC39;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Succinyl-CoA--L-malate CoA-transferase beta subunit;
DE            EC=2.8.3.22;
GN   Name=smtB; OrderedLocusNames=Caur_0178;
OS   Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC   Bacteria; Chloroflexi; Chloroflexia; Chloroflexales; Chloroflexineae;
OC   Chloroflexaceae; Chloroflexus.
OX   NCBI_TaxID=324602;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29366 / DSM 635 / J-10-fl;
RX   PubMed=21714912; DOI=10.1186/1471-2164-12-334;
RA   Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J.,
RA   Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W.,
RA   Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.;
RT   "Complete genome sequence of the filamentous anoxygenic phototrophic
RT   bacterium Chloroflexus aurantiacus.";
RL   BMC Genomics 12:334-334(2011).
CC   -!- FUNCTION: Involved in the 3-hydroxypropionate cycle used for
CC       autotrophic carbon dioxide fixation. Catalyzes the transfer of CoA
CC       moiety from succinyl-CoA to L-malate to yield L-malyl-CoA (By
CC       similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + succinyl-CoA = (S)-malyl-CoA + succinate;
CC         Xref=Rhea:RHEA:38255, ChEBI:CHEBI:15589, ChEBI:CHEBI:30031,
CC         ChEBI:CHEBI:57292, ChEBI:CHEBI:57317; EC=2.8.3.22;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(3S)-citramalate + succinyl-CoA = (3S)-citramalyl-CoA +
CC         succinate; Xref=Rhea:RHEA:38287, ChEBI:CHEBI:30031,
CC         ChEBI:CHEBI:30936, ChEBI:CHEBI:57292, ChEBI:CHEBI:58668; EC=2.8.3.22;
CC   -!- SUBUNIT: Forms a large complex composed of six heterodimers (alpha,
CC       beta). {ECO:0000250}.
CC   -!- INDUCTION: Under autotrophic growth conditions. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CoA-transferase III family. {ECO:0000305}.
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DR   EMBL; CP000909; ABY33432.1; -; Genomic_DNA.
DR   RefSeq; WP_012256088.1; NC_010175.1.
DR   RefSeq; YP_001633821.1; NC_010175.1.
DR   AlphaFoldDB; A9WC39; -.
DR   SMR; A9WC39; -.
DR   STRING; 324602.Caur_0178; -.
DR   EnsemblBacteria; ABY33432; ABY33432; Caur_0178.
DR   KEGG; cau:Caur_0178; -.
DR   PATRIC; fig|324602.8.peg.206; -.
DR   eggNOG; COG1804; Bacteria.
DR   HOGENOM; CLU_033975_2_0_0; -.
DR   InParanoid; A9WC39; -.
DR   OMA; PGAMEGW; -.
DR   BioCyc; MetaCyc:MON-13600; -.
DR   Proteomes; UP000002008; Chromosome.
DR   GO; GO:0008410; F:CoA-transferase activity; ISS:UniProtKB.
DR   GO; GO:0047370; F:succinate-citramalate CoA-transferase activity; IEA:RHEA.
DR   GO; GO:0043427; P:carbon fixation by 3-hydroxypropionate cycle; ISS:UniProtKB.
DR   Gene3D; 3.30.1540.10; -; 1.
DR   Gene3D; 3.40.50.10540; -; 1.
DR   InterPro; IPR003673; CoA-Trfase_fam_III.
DR   InterPro; IPR044855; CoA-Trfase_III_dom3_sf.
DR   InterPro; IPR023606; CoA-Trfase_III_dom_1_sf.
DR   Pfam; PF02515; CoA_transf_3; 1.
DR   SUPFAM; SSF89796; SSF89796; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation; Reference proteome; Transferase.
FT   CHAIN           1..405
FT                   /note="Succinyl-CoA--L-malate CoA-transferase beta subunit"
FT                   /id="PRO_0000429594"
FT   ACT_SITE        175
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   405 AA;  44384 MW;  58041E71692E2F4E CRC64;
     MDGTTTTLPL AGIRVIDAAT VIAAPFCATL LGEFGADVLK VEHPIGGDAL RRFGTPTARG
     DTLTWLSESR NKRSVTLNLQ HPEGARVFKE LIAHSDVLCE NFRPGTLEKW GLGWDVLSKI
     NPRLIMLRVT GYGQTGPYRD RPGFARIAHA VGGIAYLAGM PKGTPVTPGS TTLADYMTGL
     YGCIGVLLAL RHREQTGRGQ YIDAALYESV FRCSDELVPA YGMYRKVRER HGSHYNEFAC
     PHGHFQTKDG KWVAISCATD KLFARLANAM GRPELASSSV YGDQKVRLAH ASDVNEIVRD
     WCSSLTRAEV LERCYATATP AAPLNDIADF FGDRHVHARR NLVAIDAEDL GETLIMPNVV
     PKLSETPGSI RSLGPKLGEH TEEVLKEILG MCDEQINDLR SKRVI