SMZ_ARATH
ID SMZ_ARATH Reviewed; 346 AA.
AC Q6PV68; Q9SV47;
DT 21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=AP2-like ethylene-responsive transcription factor SMZ;
DE AltName: Full=Protein SCHLAFMUTZE;
GN Name=SMZ; OrderedLocusNames=At3g54990; ORFNames=F28P10.30;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, AND INDUCTION.
RX PubMed=14573523; DOI=10.1242/dev.00842;
RA Schmid M., Uhlenhaut N.H., Godard F., Demar M., Bressan R., Weigel D.,
RA Lohmann J.U.;
RT "Dissection of floral induction pathways using global expression
RT analysis.";
RL Development 130:6001-6012(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
RA Pan Y., Gong W., Liu D., Fu Q., Mei W.-Q., Song W.-Q., Ma L.-G., Luo J.-C.,
RA Deng X.-W., Zhu Y.-X.;
RT "Molecular cloning, expression, phylogenetic and functional
RT characterization of the Arabidopsis AP2/EREBP transcription factor
RT family.";
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
CC -!- FUNCTION: Probably acts as a transcriptional activator. Binds to the
CC GCC-box pathogenesis-related promoter element. May be involved in the
CC regulation of gene expression by stress factors and by components of
CC stress signal transduction pathways (By similarity). Repressor of
CC flowering. {ECO:0000250, ECO:0000269|PubMed:14573523}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q6PV68-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q6PV68-2; Sequence=VSP_027411, VSP_027412;
CC -!- INDUCTION: Repressed by miR172 after photoperiod changement.
CC {ECO:0000269|PubMed:14573523}.
CC -!- MISCELLANEOUS: 'Schlafmuetze' means 'nightcap' in German.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. AP2
CC subfamily. {ECO:0000305}.
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DR EMBL; AY576275; AAS88428.1; -; mRNA.
DR EMBL; AY560886; AAT44953.1; -; mRNA.
DR EMBL; AL049655; CAB41085.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE79323.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE79324.1; -; Genomic_DNA.
DR EMBL; BT026352; ABH04459.1; -; mRNA.
DR PIR; T06721; T06721.
DR RefSeq; NP_001078290.1; NM_001084821.1. [Q6PV68-2]
DR RefSeq; NP_191059.2; NM_115356.2. [Q6PV68-1]
DR AlphaFoldDB; Q6PV68; -.
DR SMR; Q6PV68; -.
DR BioGRID; 9980; 6.
DR IntAct; Q6PV68; 5.
DR STRING; 3702.AT3G54990.1; -.
DR PaxDb; Q6PV68; -.
DR PRIDE; Q6PV68; -.
DR ProteomicsDB; 228454; -. [Q6PV68-1]
DR EnsemblPlants; AT3G54990.1; AT3G54990.1; AT3G54990. [Q6PV68-1]
DR EnsemblPlants; AT3G54990.2; AT3G54990.2; AT3G54990. [Q6PV68-2]
DR GeneID; 824664; -.
DR Gramene; AT3G54990.1; AT3G54990.1; AT3G54990. [Q6PV68-1]
DR Gramene; AT3G54990.2; AT3G54990.2; AT3G54990. [Q6PV68-2]
DR KEGG; ath:AT3G54990; -.
DR Araport; AT3G54990; -.
DR TAIR; locus:2082732; AT3G54990.
DR eggNOG; ENOG502R1D7; Eukaryota.
DR InParanoid; Q6PV68; -.
DR OMA; AGDACIT; -.
DR OrthoDB; 1171664at2759; -.
DR PhylomeDB; Q6PV68; -.
DR PRO; PR:Q6PV68; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q6PV68; baseline and differential.
DR Genevisible; Q6PV68; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0009658; P:chloroplast organization; IMP:TAIR.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 1.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 2: Evidence at transcript level;
KW Activator; Alternative splicing; DNA-binding; Ethylene signaling pathway;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..346
FT /note="AP2-like ethylene-responsive transcription factor
FT SMZ"
FT /id="PRO_0000297943"
FT DNA_BIND 122..178
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT VAR_SEQ 239..247
FT /note="GWDAAAIKY -> YHFVRHVIF (in isoform 2)"
FT /evidence="ECO:0000303|Ref.2, ECO:0000303|Ref.5"
FT /id="VSP_027411"
FT VAR_SEQ 248..346
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.2, ECO:0000303|Ref.5"
FT /id="VSP_027412"
SQ SEQUENCE 346 AA; 38672 MW; 11BFD9D3349C8DF5 CRC64;
MLDLNLKIFS SYNEDQDRKV PLMISTTGEE ESNSSSSSTT DSAARDAFIA FGILKRDDDL
VPPPPPPPHK ETGDLFPVVA DARRNIEFSV EDSHWLNLSS LQRNTQKMVK KSRRGPRSRS
SQYRGVTFYR RTGRWESHIW DCGKQVYLGG FDTAYAAARA YDRAAIKFRG LDADINFVVD
DYRHDIDKMK NLNKVEFVQT LRRESASFGR GSSKYKGLAL QKCTQFKTHD QIHLFQNRGW
DAAAIKYNEL GKGEGAMKFG AHIKGNGHND LELSLGISSS SESIKLTTGD YYKGINRSTM
GLYGKQSSIF LPMATMKPLK TVAASSGFPF ISMTSSSSSM SNCFDP
