ID   SN12L_PONAB             Reviewed;         619 AA.
AC   Q5RCZ8;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=Schlafen family member 12-like;
GN   Name=SLFN12L;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the Schlafen family. {ECO:0000305}.
CC   -!- CAUTION: It is uncertain whether Met-1 or Met-33 is the initiator.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR858120; CAH90359.1; -; mRNA.
DR   RefSeq; NP_001129013.1; NM_001135541.2.
DR   AlphaFoldDB; Q5RCZ8; -.
DR   SMR; Q5RCZ8; -.
DR   STRING; 9601.ENSPPYP00000009204; -.
DR   PRIDE; Q5RCZ8; -.
DR   GeneID; 100190853; -.
DR   KEGG; pon:100190853; -.
DR   CTD; 100506736; -.
DR   eggNOG; ENOG502RU3F; Eukaryota.
DR   InParanoid; Q5RCZ8; -.
DR   OrthoDB; 211385at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.950.30; -; 1.
DR   InterPro; IPR029684; Schlafen.
DR   InterPro; IPR007421; Schlafen_AlbA_2_dom.
DR   InterPro; IPR038461; Schlafen_AlbA_2_dom_sf.
DR   PANTHER; PTHR12155; PTHR12155; 1.
DR   Pfam; PF04326; AlbA_2; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..619
FT                   /note="Schlafen family member 12-like"
FT                   /id="PRO_0000336098"
FT   TRANSMEM        598..618
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   619 AA;  70225 MW;  C506858083A5EE17 CRC64;
     MQLSEGLAAH GTRRAGKWKR TQVPLLGEEC ADMDLARKEF LLGNGLAAGK MNISIDLDTN
     YAELVLNVGR VTLGENNRRK MKDSQLRKQQ NENVSRAVCA LLNSGGGFIK AEVENEDYSY
     KKDGIGLDLE NSFSNMLPFV PNFLDFMQNG NYFHIFVKSW SLETSGPQIA TLSSSLYKRD
     VTSAKVMNAS AALEFLKDME KTGGRAYLRP ESPAKRACVD VQEESNMEAL AADFFNRTEL
     NYKEKLTFTE STHVEIKNFA TEKLLQRITE ILPQYVSAFA NTDGGYLFVG LNEDKEIIGF
     KAEKSYLTKL EEVTKNSIGK LPVHHFCVEK GTINYLCKSL GVYDKGRLCG YVYALRVERF
     CCAVFAKKPD SWHVKDNRVK QLTEKEWIQF MVDSESVCEE LPSPASTSSP VSQSCPLCEY
     INFKIQPLRY HLPGLSEKIT FAPKTLCRNL FSQHEGLKQL ICEEMGSVSK GSLIFSRSWS
     LDLGLQENHK VLCDALLISQ DKPPVLYTFH MVQDEEFKGY STQTAQTLKQ KLAKIGGYTK
     KVCVMTKIFY LSPEGKTSCQ YDLNSQVIYP ESYYWTTAQT MKDLEKALSN ILPKENQIFL
     FVCLFRFCLF VCLFVFFLR