ID   SNAPN_CAEEL             Reviewed;         122 AA.
AC   O44445;
DT   28-NOV-2012, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 2.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=SNAPIN protein homolog;
DE   AltName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 7;
DE            Short=BLOC-1 subunit 7;
GN   Name=snpn-1; ORFNames=C02B10.2;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2]
RP   IDENTIFICATION IN THE BLOC-1 COMPLEX, FUNCTION, AND INTERACTION WITH
RP   DSBN-1.
RX   PubMed=22916203; DOI=10.1371/journal.pone.0043043;
RA   Hermann G.J., Scavarda E., Weis A.M., Saxton D.S., Thomas L.L., Salesky R.,
RA   Somhegyi H., Curtin T.P., Barrett A., Foster O.K., Vine A., Erlich K.,
RA   Kwan E., Rabbitts B.M., Warren K.;
RT   "C. elegans BLOC-1 Functions in Trafficking to Lysosome-Related Gut
RT   Granules.";
RL   PLoS ONE 7:E43043-E43043(2012).
CC   -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC       complex-1 (BLOC-1) involved in gut granule biogenesis.
CC       {ECO:0000269|PubMed:22916203}.
CC   -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC       complex-1 (BLOC-1) composed at least of blos-1, blos-2, blos-4, dsbn-1,
CC       glo-2, mutd-1 and snpn-1. Interacts with dsbn-1.
CC       {ECO:0000269|PubMed:22916203}.
CC   -!- SIMILARITY: Belongs to the SNAPIN family. {ECO:0000305}.
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DR   EMBL; FO080093; CCD61164.1; -; Genomic_DNA.
DR   PIR; T32592; T32592.
DR   RefSeq; NP_500721.1; NM_068320.3.
DR   AlphaFoldDB; O44445; -.
DR   SMR; O44445; -.
DR   BioGRID; 42408; 21.
DR   ComplexPortal; CPX-479; Bloc-1 complex.
DR   STRING; 6239.C02B10.2; -.
DR   TCDB; 1.F.1.1.3; the synaptosomal vesicle fusion pore (svf-pore) family.
DR   EPD; O44445; -.
DR   PaxDb; O44445; -.
DR   PeptideAtlas; O44445; -.
DR   EnsemblMetazoa; C02B10.2.1; C02B10.2.1; WBGene00015327.
DR   GeneID; 177282; -.
DR   KEGG; cel:CELE_C02B10.2; -.
DR   UCSC; C02B10.2; c. elegans.
DR   CTD; 177282; -.
DR   WormBase; C02B10.2; CE24776; WBGene00015327; snpn-1.
DR   eggNOG; ENOG502SAX7; Eukaryota.
DR   GeneTree; ENSGT00390000008274; -.
DR   HOGENOM; CLU_135215_0_0_1; -.
DR   InParanoid; O44445; -.
DR   OMA; NMHIREL; -.
DR   OrthoDB; 1532513at2759; -.
DR   PhylomeDB; O44445; -.
DR   Reactome; R-CEL-432722; Golgi Associated Vesicle Biogenesis.
DR   PRO; PR:O44445; -.
DR   Proteomes; UP000001940; Chromosome IV.
DR   Bgee; WBGene00015327; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0031082; C:BLOC complex; IC:ComplexPortal.
DR   GO; GO:0031083; C:BLOC-1 complex; IBA:GO_Central.
DR   GO; GO:0099078; C:BORC complex; IBA:GO_Central.
DR   GO; GO:0008021; C:synaptic vesicle; IBA:GO_Central.
DR   GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; IBA:GO_Central.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0032418; P:lysosome localization; IBA:GO_Central.
DR   GO; GO:0007040; P:lysosome organization; IBA:GO_Central.
DR   GO; GO:1904757; P:positive regulation of gut granule assembly; IC:ComplexPortal.
DR   GO; GO:0090316; P:positive regulation of intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:2000300; P:regulation of synaptic vesicle exocytosis; IBA:GO_Central.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; IBA:GO_Central.
DR   InterPro; IPR017246; Snapin.
DR   InterPro; IPR028119; Snapin/Pallidin/Snn1.
DR   PANTHER; PTHR31305; PTHR31305; 1.
DR   Pfam; PF14712; Snapin_Pallidin; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..122
FT                   /note="SNAPIN protein homolog"
FT                   /id="PRO_0000420201"
FT   COILED          76..109
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   122 AA;  13820 MW;  02E44A4F928A01DB CRC64;
     MSSTAGGEVS INSGDLLLGT LSTSITKLEQ QIRATQLSQK KLNSDCETMA EYLRDLSEYK
     QPVDLLPYVG KLNDSTIRVN NTHQKLDDLL ERLTKLQRQI ARETYKKKNS IKEQEPPVQP
     EN