ID   ABGA_CLOLO              Reviewed;         473 AA.
AC   Q46130;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=6-phospho-beta-glucosidase;
DE            EC=3.2.1.86;
GN   Name=abgA;
OS   Clostridium longisporum.
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1523;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=B6405;
RA   Brown G.D., Thomson J.A.;
RL   Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=6-phospho-beta-D-glucosyl-(1->4)-D-glucose + H2O = D-glucose +
CC         D-glucose 6-phosphate; Xref=Rhea:RHEA:10772, ChEBI:CHEBI:4167,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:58312, ChEBI:CHEBI:61548; EC=3.2.1.86;
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 1 family. {ECO:0000305}.
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DR   EMBL; L49336; AAC05714.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q46130; -.
DR   SMR; Q46130; -.
DR   CAZy; GH1; Glycoside Hydrolase Family 1.
DR   GO; GO:0008706; F:6-phospho-beta-glucosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0103047; F:methyl beta-D-glucoside 6-phosphate glucohydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   InterPro; IPR001360; Glyco_hydro_1.
DR   InterPro; IPR018120; Glyco_hydro_1_AS.
DR   InterPro; IPR033132; Glyco_hydro_1_N_CS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10353; PTHR10353; 1.
DR   Pfam; PF00232; Glyco_hydro_1; 1.
DR   PRINTS; PR00131; GLHYDRLASE1.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   PROSITE; PS00572; GLYCOSYL_HYDROL_F1_1; 1.
DR   PROSITE; PS00653; GLYCOSYL_HYDROL_F1_2; 1.
PE   3: Inferred from homology;
KW   Glycosidase; Hydrolase.
FT   CHAIN           1..473
FT                   /note="6-phospho-beta-glucosidase"
FT                   /id="PRO_0000063894"
FT   ACT_SITE        174
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        366
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10055"
SQ   SEQUENCE   473 AA;  54414 MW;  9862BA0023903ECD CRC64;
     MSFDLSFPKS FLWGGATAAN QFEGAYNEDG KGLSIQDIAP KGVMGPITEV PTEDNMKLIG
     IDFYHRYKED IKLFAEMGFK TFRLSIAWSR IFPNGDDEIP NEKGLEFYDK VFDELQRYGI
     EPLVTLSHYE TPLNLSKKYN GWANRDLIGF YERYVRTVFT RYKDKVKYWL TFNEINSAIH
     APYMSAGIWT DKSELSKQDL YQAMHHELVA SALAVKIGHE INPDFKIGCM ILGIPVYPLT
     PHPDDLIEKM RVERESLFFA DVHARGKYPR YMNRLFKENN IEIKWHEDDA EILSNVVDFI
     SFSYYMSSCA TADEEKKKAG AGNLLAGVPN PYLKASEWGW QIDPKGLRLI LNELYDRYEK
     PLFIVENGLG AVDELVTDEN GNKTVNDDYR IKYLNDHLVQ VAEAIEDGVE LMGYTTWGCI
     DLVSASTAEL KKRYGFIYVD RHDDGSGTLE RYKKKSFNWY KEVIATNGKS LER